Evidence map›Paper›PMID 38068349›Full record

ArticleJournal of clinical medicine2023

Local MRI before and after Tumor Resection in Neuroblastoma: Impact of Residual Disease on Event Free Survival.

Jürgen F Schäfer, Sebastian Gassenmaier, Steven Warmann, Cristian Urla, Leonie Frauenfeld, Tim Flaadt, Maryanna Chaika, Michael Esser, Ilias Tsiflikas, Beate Timmermann and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Jürgen F SchäferDivision of Pediatric Radiology, Department of Radiology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0003-3279-8726
Sebastian GassenmaierDivision of Pediatric Radiology, Department of Radiology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0003-3701-2227
Steven WarmannDepartment of Pediatric Surgery and Pediatric Urology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0001-5522-3250
Cristian UrlaDepartment of Pediatric Surgery and Pediatric Urology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0001-8909-0484
Leonie FrauenfeldDepartment of Pathology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0003-4236-5799
Tim FlaadtDepartment of Pediatric Oncology and Hematology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-2729-9941
Maryanna ChaikaDivision of Pediatric Radiology, Department of Radiology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-6582-5105
Michael EsserDivision of Pediatric Radiology, Department of Radiology, University Hospital Tübingen, 72076 Tübingen, Germany.
Ilias TsiflikasDivision of Pediatric Radiology, Department of Radiology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0001-7166-4689
Beate TimmermannParticle Therapy Clinic and the West German Proton Therapy Centre, University Hospital Essen, 45147 Essen, Germany.ORCID 0000-0003-2274-2008
Jörg FuchsDepartment of Pediatric Surgery and Pediatric Urology, University Hospital Tübingen, 72076 Tübingen, Germany.
University Children's Hospital Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The study aimed to investigate the influence of MRI-defined residual disease on local tumor control after resection of neuroblastic tumors in patients without routine adjuvant radiotherapy. (2) Methods: Patients, who underwent tumor resection between 2009 and 2019 and received a pre- and postoperative MRI, were included in this retrospective single-center study. Measurement of residual disease (RD) was performed using standardized criteria. Primary endpoint was the local or combined (local and metastatic) event free survival (EFS). (3) Results: Forty-one patients (20 female) with median age of 39 months were analyzed. Risk group analysis showed eleven low-, eight intermediate-, and twenty-two high-risk patients (LR, IR, HR). RD was found in 16 cases by MRI. A local or combined relapse or progression was found in nine patients of whom eight patients had RD (

Indexed as

EFShigh-risk neuroblastomairradiationMRIresidual tumorsurgical resection

Identifiers

PMID38068349
PMCPMC10707530
OpenAlexW4388969058

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.