Evidence map›Paper›PMID 38068316›Full record

ArticleJournal of clinical medicine2023

What Else Is Needed to Improve Survival from Out-of-Hospital Cardiac Arrest to Hospital Admission? Data from a Prospective Registry for the Years 2020-2023 in the Italian Province of Varese.

Roberto De Ponti, Carlo Arnò, Andrea Piemonti, Paola Centineo, Paola Genoni, Michele Golino, Simone Savastano, Guido Garzena, Sabina Campi

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 68% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Roberto De PontiDepartment of Medicine and Surgery, University of Insubria-Varese, Cardiology Unit, Ospedale di Circolo, ASST Settelaghi, 21100 Varese, Italy.ORCID 0000-0003-3278-1721
Carlo ArnòDepartment of Medicine and Surgery, University of Insubria-Varese, Cardiology Unit, Ospedale di Circolo, ASST Settelaghi, 21100 Varese, Italy.
Andrea PiemontiDepartment of Medicine and Surgery, University of Insubria-Varese, Cardiology Unit, Ospedale di Circolo, ASST Settelaghi, 21100 Varese, Italy.
Paola CentineoAgenzia Regionale Emergenza Urgenza, Articolazione Aziendale Territoriale-118 Varese, 21100 Varese, Italy.
Paola GenoniDepartment of Medicine and Surgery, University of Insubria-Varese, Cardiology Unit, Ospedale di Circolo, ASST Settelaghi, 21100 Varese, Italy.
Michele GolinoDepartment of Medicine and Surgery, University of Insubria-Varese, Cardiology Unit, Ospedale di Circolo, ASST Settelaghi, 21100 Varese, Italy.ORCID 0000-0003-0141-0127
Simone SavastanoCardiology Unit, IRCCS Fondazione Policlinico S. Matteo, 27100 Pavia, Italy.ORCID 0000-0002-9789-6661
Guido GarzenaAgenzia Tutela della Salute Insubria, 21100 Varese, Italy.
Sabina CampiAgenzia Regionale Emergenza Urgenza, Articolazione Aziendale Territoriale-118 Varese, 21100 Varese, Italy.
University of Insubria · ITAgenzia Regionale Emergenza Urgenza · ITPoliclinico San Matteo Fondazione · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Around the world, data on out-of-hospital cardiac arrest (OHCA) are heterogeneous in terms of outcomes and reporting, and not all registries follow the Utstein recommendations for uniform OHCA data collection. This study reports data on OHCA occurring in recent years in a limited territory to analyze, in a homogenous setting, the circumstances and interventions affecting survival to hospital admission. OHCA data from the province of Varese for the years 2020-2022 were extracted from a prospective registry. For survival to hospital admission, the impact of pandemic waves and variables known to affect survival was evaluated both in the overall population and in the subgroup of patients in whom cardiopulmonary resuscitation (CPR) was initiated or continued by the emergency medical service (EMS). Overall, 3263 OHCAs occurred mainly at home (88%), with a time to intervention of 13.7 min, which was significantly longer during lockdown (15.7 min). Bystanders performed CPR in 22% of the cases and used automatic external defibrillator (AED) in 2.2% of the cases. Overall survival to hospital admission was 7.7%. In the multivariate analysis, in the general population, occurrence near a public building (OR 1.92), the presence of witnesses (OR 2.65), and a shockable rhythm (OR 7.04) were independent predictors of survival to hospital admission, whereas age (OR 0.97) and occurrence during a pandemic wave (OR 0.62) were associated with significantly worse survival to hospital admission. In the group of patients who received CPR, AED shock by bystanders was the only independent predictor of survival (OR 3.14) to hospital admission. Among other factors, early defibrillation was of crucial importance to improve survival to hospital admission in possibly rescuable patients. The occurrence of OHCA during pandemic waves was associated with longer intervention time and worse survival to hospital admission.

Indexed as

COVID-19 pandemicout-of-hospital cardiac arrestsudden cardiac deathventricular fibrillation

Identifiers

PMID38068316
PMCPMC10706880
OpenAlexW4388939268

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.