Evidence map›Paper›PMID 38068307›Full record

ArticleJournal of clinical medicine2023

A Prior History of Cryptozoospermia Is Associated with a Significantly Higher Chance of a Successful Microdissection Testicular Sperm Extraction Compared to Non-Obstructive Azoospermia.

James Wren, Matthew Hudnall, Minh Pham, Anne L Darves-Bornoz, Joshua A Halpern, Nelson E Bennett, Robert E Brannigan, Matthias D Hofer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

James WrenDepartment of Urology, Northwestern University Feinberg School of Medicine, 676 North St. Clare St., Arkes Pavilion 23-025, Chicago, IL 60611, USA.ORCID 0000-0002-2028-1132
Matthew HudnallDepartment of Urology, Northwestern University Feinberg School of Medicine, 676 North St. Clare St., Arkes Pavilion 23-025, Chicago, IL 60611, USA.
Minh PhamDepartment of Urology, Northwestern University Feinberg School of Medicine, 676 North St. Clare St., Arkes Pavilion 23-025, Chicago, IL 60611, USA.
Anne L Darves-BornozDepartment of Urology, Northwestern University Feinberg School of Medicine, 676 North St. Clare St., Arkes Pavilion 23-025, Chicago, IL 60611, USA.
Joshua A HalpernDepartment of Urology, Northwestern University Feinberg School of Medicine, 676 North St. Clare St., Arkes Pavilion 23-025, Chicago, IL 60611, USA.
Nelson E BennettDepartment of Urology, Northwestern University Feinberg School of Medicine, 676 North St. Clare St., Arkes Pavilion 23-025, Chicago, IL 60611, USA.
Robert E BranniganDepartment of Urology, Northwestern University Feinberg School of Medicine, 676 North St. Clare St., Arkes Pavilion 23-025, Chicago, IL 60611, USA.
Matthias D HoferDepartment of Urology, Northwestern University Feinberg School of Medicine, 676 North St. Clare St., Arkes Pavilion 23-025, Chicago, IL 60611, USA.
Northwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur study sought to evaluate the rates of successful sperm retrieval following microdissection testicular sperm extraction (mTESE) in patients with a prior history of cryptozoospermia, compared to patients with non-obstructive azoospermia (NOA).

methodsA retrospective chart analysis evaluating all mTESE procedures was performed from January 2004 to August 2018. Inclusion criteria involved all males >18 years of age with a diagnosis of cryptozoospermia and/or NOA that underwent a mTESE. The patient's genetic profile, hormonal profile, semen analysis, testicular volumes, pathology and comorbidities were analyzed.

resultsWe identified 40 patients with cryptozoospermia and 221 patients with NOA. Successful mTESE occurred in 34/40 (85%) cryptozoospermic males compared to 104/221 (48%) NOA males (

conclusionDespite patients with a history of cryptozoospermia having a significantly higher chance of a successful sperm retrieval than patients with NOA, couples should be counselled on the possibility of an unsuccessful sperm extraction, in order to optimize the pre-operative IVF planning and to manage operative expectations.

Indexed as

azoospermiacryptozoospermiamicrodissection testicular sperm extraction

Identifiers

PMID38068307
PMCPMC10706993
OpenAlexW4388942127

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.