ArticleJournal of clinical medicine2023
Sex-Specific Disparities in Outcomes of Transcatheter Edge-to-Edge Repair for Mitral Regurgitation: A Multicenter "Real-World" Analysis.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 12 citations in OpenAlex.
- Influence of age, frailty and non-cardiac comorbidities on survival in patients undergoing mitral valve edge-to-edge repair - a perspective from the German health care system.International journal of cardiology. Heart & vasculature · 2026Article
- Sex-Specific Outcomes in Patients Undergoing Mitral Valve Transcatheter Edge-to-Edge Repair: The REPAIR Study.JACC. Advances · 2026Article
- Sex and Racial Disparities in Outcomes of Transcatheter Edge-to-Edge Mitral Valve Repair for Functional Mitral Regurgitation: A Multicenter Prospective Analysis.Structural heart : the journal of the Heart Team · 2026Article
- Women's cardiovascular health in 2025:Saudi medical journal · 2026Review
- The Influence of Left Ventricular Ejection Fraction on Long-Term Survival of Patients after Transcatheter Edge-to-Edge Mitral Valve Repair.Cardiology · 2026Article
- Gender Matters: A State-of-the-Art Review of Transcatheter Structural Interventions in Older Women Vs Men.JACC. Advances · 2025Article
- Sex-Specific Outcomes of Transcatheter Edge-to-Edge Repair for Degenerative Mitral Regurgitation: Results From the CLASP IID Trial.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Inpatient Outcomes of Tricuspid Transcatheter Edge-to-Edge Repair in the United States Based on Sex.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Predicting the Need for Intensive Care Unit Treatment After Successful Transcatheter Edge-to-Edge Mitral Valve Repair.Journal of clinical medicine · 2025Article
- To clip or not to clip? A review of precise risk assessment in the contemporary era of transcatheter edge-to-edge mitral and tricuspid valve repair.Frontiers in cardiovascular medicine · 2025Review
- Identifying Responders to Transcatheter Interventions for Secondary Mitral Regurgitation.Current treatment options in cardiovascular medicine · 2025Review
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundmitral regurgitation (mr) is the most common valvular heart disease (vhd) in the elderly and tends to be more prevalent in women. while relevant sex differences in outcomes are evident in surgically treated collectives, there are very limited and conflicting sex-specific data for the growing cohort of patients undergoing transcatheter edge-to-edge repair (teer).
objectiveto investigate whether sex impacts procedural safety and efficacy, and in-hospital- and long-term outcomes, after teer for mr.
methodsin a multicenter observational cohort study, patients who underwent teer were stratified by sex and relevant outcome measures, and analyzed using multivariable cox regression and propensity score matching (psm).
resultsa total of 821 patients were analyzed, of whom 37.4% (307/821) were female. compared to male patients, females were significantly older (77 ± 8.5 vs. 80.4 ± 6.7 years,
conclusionsfemale patients are older and less comorbid than males undergoing TEER. The TEER procedure is equally safe and effective in both sexes. While in-hospital mortality did not differ, female patients experienced a significantly better adjusted long-term survival compared to male patients. Concomitant AF offsets the prognostic advantage of females over males and, in contrast to males, significantly impairs long-term survival in women undergoing TEER. Further research is warranted to elucidate underlying causes for the observed sex disparities and to develop sex-tailored treatment recommendations.
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