Evidence map›Paper›PMID 38068251›Full record

ReviewJournal of clinical medicine2023

Oligometastatic Prostate Cancer-The Middle Child Syndrome.

Ee Jean Lim, Mengyue Su, B M Saiduzzaman, Kae Jack Tay, Henry Sun Sien Ho, Theodoros Tokas, Bhaskar Kumar Somani, Vineet Gauhar, John Shyi Peng Yuen, Kenneth Chen

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ee Jean LimDepartment of Urology, Singapore General Hospital, Singapore 169608, Singapore.ORCID 0000-0002-5242-0651
Mengyue SuDepartment of Urology, Singapore General Hospital, Singapore 169608, Singapore.
B M SaiduzzamanDepartment of Urology, Singapore General Hospital, Singapore 169608, Singapore.ORCID 0009-0002-8908-2753
Kae Jack TayDepartment of Urology, Singapore General Hospital, Singapore 169608, Singapore.
Henry Sun Sien HoDepartment of Urology, Singapore General Hospital, Singapore 169608, Singapore.
Theodoros TokasDepartment of Urology, University General Hospital of Heraklion, University of Crete, Medical School, 14122 Heraklion, Greece.ORCID 0000-0003-0928-0507
Bhaskar Kumar SomaniDepartment of Urology, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.ORCID 0000-0002-6248-6478
Vineet GauharDepartment of Urology, Ng Teng Fong Hospital, Singapore 609606, Singapore.ORCID 0000-0002-3740-7141
John Shyi Peng YuenDepartment of Urology, Singapore General Hospital, Singapore 169608, Singapore.
Kenneth ChenDepartment of Urology, Singapore General Hospital, Singapore 169608, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oligometastatic prostate cancer is an evolving clinical entity as more data from novel imaging tools such as PSMA PET/CT emerges. Recognition of this disease entity allows for unique interventions which differ from conventional treatment of metastatic prostate cancers such as the initiation of chemotherapy. With metastasis-directed therapy (MDT), there is potential for early eradication of limited disease metastases and a delay in systemic treatment with its associated treatment-related toxicities. This review explores the current evidence and outcomes of different metastasis-directed therapies such as the role of radiotherapy in low volume metastasis and the use of PSMA ligands to facilitate pelvic lymph node dissections. With a deeper understanding of this low metastasis state, it has revolutionized the current viable treatment options, and more studies are ongoing to provide further insights into this unique disease entity.

Indexed as

imagingmetastasis-directed therapyoligometastatic prostate cancer (OMPC)

Identifiers

PMID38068251
PMCPMC10706851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.