Evidence map›Paper›PMID 38067613›Full record

ArticleMolecules (Basel, Switzerland)2023

Cellulose Nanocrystal-Based Emulsion of Thyme Essential Oil: Preparation and Characterisation as Sustainable Crop Protection Tool.

Francesca Baldassarre, Daniele Schiavi, Veronica Di Lorenzo, Francesca Biondo, Viviana Vergaro, Gianpiero Colangelo, Giorgio Mariano Balestra, Giuseppe Ciccarella

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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  7. Droplet Digital PCR for the Detection ofPlants (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Francesca BaldassarreDepartment of Biological and Environmental Sciences, UdR INSTM of Lecce University of Salento, Via Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-3328-7701
Daniele SchiaviDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Via S. Camillo de Lellis, snc, 01100 Viterbo, Italy.ORCID 0000-0003-2743-6413
Veronica Di LorenzoDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Via S. Camillo de Lellis, snc, 01100 Viterbo, Italy.
Francesca BiondoDepartment of Biological and Environmental Sciences, UdR INSTM of Lecce University of Salento, Via Monteroni, 73100 Lecce, Italy.
Viviana VergaroDepartment of Biological and Environmental Sciences, UdR INSTM of Lecce University of Salento, Via Monteroni, 73100 Lecce, Italy.ORCID 0000-0003-3706-6276
Gianpiero ColangeloDepartment of Engineering for Innovation, University of Salento, Via Monteroni, 73100 Lecce, Italy.ORCID 0000-0001-9182-4336
Giorgio Mariano BalestraDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Via S. Camillo de Lellis, snc, 01100 Viterbo, Italy.ORCID 0000-0002-0822-4506
Giuseppe CiccarellaDepartment of Biological and Environmental Sciences, UdR INSTM of Lecce University of Salento, Via Monteroni, 73100 Lecce, Italy.ORCID 0000-0003-4467-0922
University of Salento · ITUniversità degli Studi della Tuscia · IT

Funding

MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA, Italy ARS01_01002 CUP: F36C18000180005Regione Puglia 0B988883
6 · The paper itself

Abstract

Essential oil-based pesticides, which contain antimicrobial and antioxidant molecules, have potential for use in sustainable agriculture. However, these compounds have limitations such as volatility, poor water solubility, and phytotoxicity. Nanoencapsulation, through processes like micro- and nanoemulsions, can enhance the stability and bioactivity of essential oils. In this study, thyme essential oil from supercritical carbon dioxide extraction was selected as a sustainable antimicrobial tool and nanoencapsulated in an oil-in-water emulsion system. The investigated protocol provided high-speed homogenisation in the presence of cellulose nanocrystals as stabilisers and calcium chloride as an ionic crosslinking agent. Thyme essential oil was characterised via GC-MS and UV-vis analysis, indicating rich content in phenols. The cellulose nanocrystal/essential oil ratio and calcium chloride concentration were varied to tune the nanoemulsions' physical-chemical stability, which was investigated via UV-vis, direct observation, dynamic light scattering, and Turbiscan analysis. Transmission electron microscopy confirmed the nanosized droplet formation. The nanoemulsion resulting from the addition of crosslinked nanocrystals was very stable over time at room temperature. It was evaluated for the first time on

Indexed as

Anti-Infective AgentsNanoparticlesOils, VolatileThymus PlantCalcium ChlorideCelluloseCrop ProtectionEmulsionsPlant OilsThymolWaterAnti-Infective AgentsCalcium ChlorideCelluloseEmulsionsOils, VolatilePlant Oilsthyme oilThymolWaterbiopesticidescellulose nanocrystalsnanoemulsionsolive knot diseasephenolsthyme essential oil

Identifiers

PMID38067613
PMCPMC10707935
OpenAlexW4389238277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.