Evidence map›Paper›PMID 38067505›Full record

ArticleMolecules (Basel, Switzerland)2023

Azorean Black Tea (

Chantal Fernandes, José Sousa-Baptista, Ana Filipa Lenha-Silva, Daniela Calheiros, Edmilson Correia, Artur Figueirinha, Lígia Salgueiro, Teresa Gonçalves

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. VdAHA1 positively regulate pathogenicity inFrontiers in microbiology · 2025
    Article
  3. Caffeine Protects Keratinocytes fromInternational journal of molecular sciences · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chantal FernandesCNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.
José Sousa-BaptistaCNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.
Ana Filipa Lenha-SilvaCNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.ORCID 0000-0002-2112-1798
Daniela CalheirosCNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.ORCID 0000-0001-8852-8771
Edmilson CorreiaCNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.ORCID 0000-0003-3265-954X
Artur FigueirinhaFaculty of Pharmacy, Health Sciences Campus, University of Coimbra, Azinhaga de S. Comba, 3000-548 Coimbra, Portugal.ORCID 0000-0003-3064-5718
Lígia SalgueiroFaculty of Pharmacy, Health Sciences Campus, University of Coimbra, Azinhaga de S. Comba, 3000-548 Coimbra, Portugal.ORCID 0000-0003-0948-821X
Teresa GonçalvesCNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.ORCID 0000-0001-9347-0535
University of Coimbra · PTUniversidade do Porto · PT

Funding

European Regional Development Fund (ERDF) CENTRO-01-0145-FEDER- 000012- HealthyAging2020 and CENTRO-01-0145-FEDER- 022095: ViraVector; the COMPETE 2020 - Operational Programme for Competitiveness and Internation-alisationPortuguese national funds via FCT - Fundação para a Ciência e a Tecnolo-gia,I.P. UIDB/04539/2020 and UIDP/04539/2020
6 · The paper itself

Abstract

The treatment of dermatophytoses, the most common human fungal infections, requires new alternatives. The aim of this study was to determine the antidermatophytic activity of the aqueous Azorean Black Tea extract (ABT), together with an approach to the mechanisms of action. The phytochemical analysis of ABT extract was performed by HPLC. The dermatophytes susceptibility was assessed using a broth microdilution assay; potential synergies with terbinafine and griseofulvin were evaluated by the checkerboard assay. The mechanism of action was appraised by the quantification of the fungal cell wall chitin and β-1,3-glucan, and by membrane ergosterol. The presence of ultrastructural modifications was studied by Transmission Electron Microscopy (TEM). The ABT extract contained organic and phenolic acids, flavonoids, theaflavins and alkaloids. It showed an antidermatophytic effect, with MIC values of 250 µg/mL for

Indexed as

ArthrodermataceaeCamellia sinensisFungicides, IndustrialMycosesAntifungal AgentsHumansMicrobial Sensitivity TestsPlant ExtractsTeaTerbinafineTrichophytonAntifungal AgentsFungicides, IndustrialPlant ExtractsTeaTerbinafineantidermatophyticantifungalAzorean Black TeaCamellia sinensiscell wallchitindermatophytesergosterolglucan

Identifiers

PMID38067505
PMCPMC10707949
OpenAlexW4389051715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.