Evidence map›Paper›PMID 38067486›Full record

ArticleMolecules (Basel, Switzerland)2023

Local Clays from China as Alternative Hemostatic Agents.

Changjiao Gan, Hongjie Hu, Zhiyun Meng, Xiaoxia Zhu, Ruolan Gu, Zhuona Wu, Wenzhong Sun, Peng Han, Hongliang Wang, Guifang Dou and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Changjiao GanDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.ORCID 0000-0002-9522-6322
Hongjie HuZhengzhou Institute of Multipurpose Utilization of Mineral Resources, Zhengzhou 450006, China.
Zhiyun MengDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Xiaoxia ZhuDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Ruolan GuDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Zhuona WuDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Wenzhong SunDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Peng HanDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Hongliang WangZhengzhou Institute of Multipurpose Utilization of Mineral Resources, Zhengzhou 450006, China.
Guifang DouDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Hui GanDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.

Funding

Beijing Municipal Natural Science Foundation(NO.7202148),Chinese National Science and Technology Key Projects for the financial assistance (2016ZX09J16103-001-001) NO.7202148, 2016ZX09J16103-001-001
6 · The paper itself

Abstract

In recent years, the coagulation properties of inorganic minerals such as kaolin and zeolite have been demonstrated. This study aimed to assess the hemostatic properties of three local clays from China: natural kaolin from Hainan, natural halloysite from Yunnan, and zeolite synthesized by our group. The physical and chemical properties, blood coagulation performance, and cell biocompatibility of the three materials were tested. The studied materials were characterized by using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), X-ray fluorescence spectroscopy (XRF), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). All three clays showed different morphologies and particle size, and exhibited negative potentials between pH 6 and 8. The TGA and DSC curves for kaolin and halloysite were highly similar. Kaolin showed the highest water absorption capacity (approximately 93.8% ± 0.8%). All three clays were noncytotoxic toward L929 mouse fibroblasts. Kaolin and halloysite showed blood coagulation effects similar to that exhibited by zeolite, indicating that kaolin and halloysite are promising alternative hemostatic materials.

Indexed as

HemostaticsZeolitesAnimalsChinaClayKaolinMiceClayHemostaticsKaolinZeolitesclayhalloysitehemostatic agentkaolinzeolite

Identifiers

PMID38067486
PMCPMC10708434

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.