Evidence map›Paper›PMID 38067441›Full record

ArticleMolecules (Basel, Switzerland)2023

Effect of Gamma Irradiation on Cannabinoid, Terpene, and Moisture Content of Cannabis Biomass.

Chandrani G Majumdar, Mahmoud A ElSohly, Elsayed A Ibrahim, Mostafa A Elhendawy, Donald Stanford, Suman Chandra, Amira S Wanas, Mohamed M Radwan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Endophytes inPlants (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Integrated Management of Pathogens and Microbes inPlants (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Chandrani G MajumdarNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
Mahmoud A ElSohlyNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
Elsayed A IbrahimNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
Mostafa A ElhendawyDepartment of Chemistry and Biochemistry, University of Mississippi, University, MS 38677, USA.
Donald StanfordNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
Suman ChandraNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.ORCID 0000-0002-2552-5546
Amira S WanasNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
Mohamed M RadwanNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
University of Mississippi · USDamietta University · EGSuez Canal University · EG

Funding

NIDA NIH HHS N01DA-15-7793
6 · The paper itself

Abstract

In recent years, cannabis has been proposed and promoted not only as a medicine for the treatment of a variety of illnesses, but also as an industrial crop for different purposes. Being an agricultural product, cannabis inflorescences may be contaminated by environmental pathogens at high concentrations, which might cause health problems if not controlled. Therefore, limits have to be placed on the levels of aerobic bacteria as well as yeast and mold. To ensure the safety of cannabis plant material and related products, a remediation process has to be put in place. Gamma irradiation is a sterilization process mainly used for pharmaceuticals, foods, cosmetics, agricultural, and herbal products including cannabis plant material. This study was designed to determine the effect of irradiation on the microbial count as well as on the chemical and physical profiles of the cannabis biomass, particularly cannabinoids, terpenes, and moisture content. The full cannabinoid profile was measured by GC/FID and HPLC analysis, while terpene profile and moisture content were determined using GC/MS and Loss on Drying (LoD) methods, respectively. Analyses were conducted on the samples before and after gamma irradiation. The results showed that the minimum and maximum doses were 15 and 20.8 KiloGray (KGY), respectively. Total Aerobic Microbial Count (TAMC) and Total Yeast and Mold Count (TYMC) were determined. The study showed that irradiation has no effect on the cannabinoids and little effect on terpenes and moisture content, but it did result in the virtual sterilization of the plant material, as evidenced by the low levels of bacterial and fungal colony-forming units (CFUs) < 10 after gamma irradiation.

Indexed as

CannabinoidsCannabisHallucinogensBiomassCannabinoid Receptor AgonistsSaccharomyces cerevisiaeTerpenesCannabinoid Receptor AgonistsCannabinoidsHallucinogensTerpenescannabinoidscannabisgamma irradiationmoisture contentterpenes

Identifiers

PMID38067441
PMCPMC10707833
OpenAlexW4388901985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.