Evidence map›Paper›PMID 38067385›Full record

ArticleCancers2023

Fractionated Photofrin-Mediated Photodynamic Therapy Significantly Improves Long-Term Survival.

Hongjing Sun, Weibing Yang, Yihong Ong, Theresa M Busch, Timothy C Zhu

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Emerging Nanoplatforms are Effective Against Tumor Hypoxia.International journal of nanomedicine · 2026
    Review
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hongjing SunDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Weibing YangDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Yihong OngDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-2826-1451
Theresa M BuschDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Timothy C ZhuDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-2842-8984
University of Pennsylvania · US

Funding

TUMOR HYPOXIA, PHOTOSENSITIZER, VASCULARITY AND PDTP01CA087971 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BUSCH, THERESA M, CENGEL, KEITH A · 2001 to 2019
$24.8M
Optimizing singlet oxygen dosimetry for photodynamic therapy (PDT)R01EB032821 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI HADFIELD, ROBERT HUGH, ZHU, TIMOTHY C. · 2022 to 2025
$2.4M
In situ PEDSy and light delivery platform for Intracavitory Photodynamic TherapyR01EB028778 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI POTASEK, MARY, ZHU, TIMOTHY C. · 2020 to 2023
$2.2M
Photodynamic therapy with prior inhibition of epidermal growth factor receptor to stimulate antitumor innate immune responseR01CA236362 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BUSCH, THERESA M · 2019 to 2023
$2.2M
NCI NIH HHS P01 CA087971NCI NIH HHS R01 CA236362NIBIB NIH HHS R01 EB028778NIBIB NIH HHS R01 EB032821NIH HHS R01 EB028778, R01 EB032821, P01 CA087971, R01 CA236362
6 · The paper itself

Abstract

This study investigates the effect of fractionated (two-part) PDT on the long-term local control rate (LCR) using the concentration of reactive oxygen species ([ROS]

Indexed as

light fractionationmacroscopic modelPDT explicit dosimetryphotodynamic therapyPhotofrinsinglet oxygen

Identifiers

PMID38067385
PMCPMC10705090
OpenAlexW4389238000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.