Evidence map›Paper›PMID 38067376›Full record

ArticleCancers2023

Rotating Night Shift Work, Sleep, and Thyroid Cancer Risk in the Nurses' Health Study 2.

Kyriaki Papantoniou, Peter Konrad, Shahab Haghayegh, Susanne Strohmaier, A Heather Eliassen, Eva Schernhammer

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Impact of sleep on gastrointestinal cancer.World journal of clinical oncology · 2024
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kyriaki PapantoniouDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-0340-9659
Peter KonradDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, 1090 Vienna, Austria.
Shahab HaghayeghChanning Division of Network Medicine, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-7232-2637
Susanne StrohmaierDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-9387-2056
A Heather EliassenChanning Division of Network Medicine, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
Eva SchernhammerDepartment of Epidemiology, Center for Public Health, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-4337-9415

Funding

Life Course Cancer Epidemiology Cohort in WomenU01CA176726 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 2018 to 2025
$22.4M
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic researchU01HL145386 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI CHAVARRO, JORGE EDUARDO, MANSON, JOANN ELISABETH · 2019 to 2025
$17.8M
Project 3: Cumulative Risk and Geospatial Health Disparities Related to Chemical and Non-Chemical Stressor ExposuresP50MD010428 · NIMHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI LADEN, FRANCINE, LEVY, JONATHAN I · 2015 to 2020
$4.0M
NCI NIH HHS U01 CA176726NHLBI NIH HHS U01 HL145386NIMHD NIH HHS P50 MD010428
6 · The paper itself

Abstract

Night shift work has been associated with breast, prostate, and colorectal cancer, but evidence on other types of cancer is limited. We prospectively evaluated the association of rotating night shift work, sleep duration, and sleep difficulty with thyroid cancer risk in the Nurses' Health Study 2 (NHS2). We assessed rotating night shift work duration (years) at baseline and throughout follow-up (1989-2015) and sleep characteristics in 2001. Cox proportional hazard models, adjusted for potential confounders, were used to calculate hazard ratios (HR) and 95% confidence intervals (CI) for (a) shift work duration, (b) sleep duration, and (c) difficulty falling or staying asleep. We stratified the analyses of night shift work by sleep duration and sleep difficulty. Over 26 years of follow-up, 588 incident cases were identified among 114,534 women in the NHS2 cohort. We observed no association between night shift work and the risk of thyroid cancer. Difficulty falling or staying asleep was suggestively associated with a higher incidence of thyroid cancer when reported sometimes (HR 1.26, 95% CI 0.95, 1.66) and all or most of the time (HR 1.35, 95% CI 1.00, 1.81). Night shift workers (10+ years) with sleep difficulty all or most of the time (HR 1.47; 0.58-3.73) or with >7 h of sleep duration (HR 2.17; 95% CI, 1.21-3.92) had a higher risk of thyroid cancer. We found modest evidence for an increased risk of thyroid cancer in relation to sleep difficulty, which was more pronounced among night shift workers.

Indexed as

night shift worksleep difficultysleep durationthyroid cancer

Identifiers

PMID38067376
PMCPMC10705158

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.