Evidence map›Paper›PMID 38067365›Full record

ArticleCancers2023

Immunoassay Urine Drug Testing among Patients Receiving Opioids at a Safety-Net Palliative Medicine Clinic.

John M Halphen, Joseph A Arthur, Soraira Pacheco, Linh M T Nguyen, Nikitha N Samy, Nathaniel R Wilson, Gregory Sattler, Shane E Wing, Rex A D Paulino, Christine Feng and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

John M HalphenJoan and Stanford Alexander Division of Geriatric and Palliative Medicine, McGovern Medical School, UTHealth, Houston, TX 77030, USA.
Joseph A ArthurDepartment of Palliative Care, Rehabilitation and Integrative Medicine, MD Anderson Cancer Center, Houston, TX 77030, USA.
Soraira PachecoJoan and Stanford Alexander Division of Geriatric and Palliative Medicine, McGovern Medical School, UTHealth, Houston, TX 77030, USA.ORCID 0000-0002-0963-0258
Linh M T NguyenJoan and Stanford Alexander Division of Geriatric and Palliative Medicine, McGovern Medical School, UTHealth, Houston, TX 77030, USA.
Nikitha N SamyMcGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.ORCID 0009-0006-7513-0004
Nathaniel R WilsonMcGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Gregory SattlerMcGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Shane E WingMcGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Rex A D PaulinoMcGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.ORCID 0009-0008-7019-0037
Christine FengMcGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Pulin ShahMcGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Simbiat OlayiwolaJoan and Stanford Alexander Division of Geriatric and Palliative Medicine, McGovern Medical School, UTHealth, Houston, TX 77030, USA.
Bradley CannellDepartment of Epidemiology, Human Genetics & Environmental Sciences, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Supriyanka AddimulamDepartment of Epidemiology, Human Genetics & Environmental Sciences, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.ORCID 0000-0001-5158-1157
Riddhi PatelDepartment of Epidemiology, Human Genetics & Environmental Sciences, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
David HuiDepartment of Palliative Care, Rehabilitation and Integrative Medicine, MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0003-2733-6607
The University of Texas Health Science Center at Houston · USThe University of Texas MD Anderson Cancer Center · US

Funding

Efficacy and Safety of Rapid-Onset Opioids for Exertional Dyspnea in Cancer PatientsR01CA231471 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HUI, DAVID · 2020 to 2024
$1.9M
Strategies for Persistent Agitated Delirium in Palliative CareR01CA225701 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HUI, DAVID · 2019 to 2022
$1.9M
A Randomized Controlled Trial of Dexamethasone for Dyspnea in Cancer PatientsR01CA214960 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HUI, DAVID · 2017 to 2020
$1.6M
NCI NIH HHS R01 CA214960NCI NIH HHS R01 CA225701NCI NIH HHS R01 CA231471
6 · The paper itself

Abstract

backgroundFew studies have examined the use of immunoassay urine drug testing of cancer patients in palliative care clinics.

objectivesWe examined the frequency of immunoassay urine drug test (UDT) abnormalities and the factors associated with aberrancy at a safety-net hospital palliative medicine clinic.

methodsA retrospective review of the electronic medical records of consecutive eligible patients seen at the outpatient palliative medicine clinic in a resource-limited safety-net hospital system was conducted between 1 September 2015 and 31 December 2020. We collected longitudinal data on patient demographics, UDT findings, and potential predictors of aberrant results.

resultsOf the 913 patients in the study, 500 (55%) underwent UDT testing, with 455 (50%) having the testing within the first three visits. Among those tested within the first three visits, 125 (27%) had aberrant UDT results; 44 (35%) of these 125 patients were positive for cocaine. In a multivariable regression model analysis of predictors for aberrant UDT within the first three visits, non-Hispanic White race (odds ratio (OR) = 2.13; 95% confidence interval (CI): 1.03-4.38;

conclusionDespite limitations of immunoassay UDT, it was able to detect aberrant drug-taking behaviors in a significant number of patients seen at a safety-net hospital palliative care clinic, including cocaine use. These findings support universal UDT monitoring and utility of immunoassay-based UDT in resource-limited settings.

Indexed as

cancer paineducationimmunoassaynonmedicalopioidpalliative medicinesafety-net hospitalurine drug test

Identifiers

PMID38067365
PMCPMC10705126
OpenAlexW4389206256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.