Evidence map›Paper›PMID 38067321›Full record

ReviewCancers2023

Review of Current Treatment Intensification Strategies for Prostate Cancer Patients.

Sobia Wasim, Jieun Park, Seungyoon Nam, Jaehong Kim

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Unlocking the Potential ofPlants (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Overdiagnosis and Overtreatment in Prostate Cancer.Diseases (Basel, Switzerland) · 2025
    Review
  10. Article
  11. Integrative genomic analysis identifiesFrontiers in pharmacology · 2025
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sobia WasimDepartment of Biochemistry, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.ORCID 0000-0002-6658-8404
Jieun ParkDepartment of Neurology, College of Medicine, Dongguk University, Goyang 10326, Republic of Korea.
Seungyoon NamDepartment of Genome Medicine and Science, College of Medicine, Gachon University, Incheon 21565, Republic of Korea.ORCID 0000-0002-0966-7915
Jaehong KimDepartment of Biochemistry, College of Medicine, Gachon University, Incheon 21999, Republic of Korea.ORCID 0000-0001-5653-1159
Gachon University · KRDongguk University · KR

Funding

National Priority Research Center Program Grant NRF-2021R1A6A1A03038865
6 · The paper itself

Abstract

Prostate cancer (PCa) used to be one of the most common nondermatologic cancers in men that can be treated only with surgery. However, a revolutionary breakthrough came in the 1980s with the introduction of long-acting luteinizing hormone-releasing hormone (LHRH) agonists for the curative treatment of PCa. This paradigm shift contributed to the combined use of androgen deprivation therapy (ADT), chemotherapy, and radiotherapy for the treatment. The latest data highlight the use of treatment intensification (TI), i.e., combined use of radiotherapy (RT) and hormonal or drug treatments, for localized or locally advanced PCa. Indeed, the results of combined modality treatments have shown a reduction in disease-specific mortality and improved overall survival. Although TI seems promising, more research studies are warranted to confirm its efficacy. This review summarizes the latest available outcome results of pivotal trials and clinical studies on the efficacy of TI.

Indexed as

ADTLHRH agonistprostate cancerradiotherapy/radiation therapytreatment intensification

Identifiers

PMID38067321
PMCPMC10705205
OpenAlexW4389100247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.