Evidence map›Paper›PMID 38067285›Full record

ReviewCancers2023

Is There a Place for Brachytherapy in Vulvar Cancer? A Narrative Review.

Sofia Cordoba, Abel Cordoba, Beatriz Gil, Raquel Benlloch, Silvia Rodriguez, Dina Najjari-Jamal, Sofía Santana, Lucie Bresson, Cristina de la Fuente, Jesús Romero

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Spanish Society for Radiation Oncology and Spanish Society of Medical Physicists recommendations on reirradiation in gynecological cancer: reirradiation techniques, survival outcomes, dose, and toxicity.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Guideline
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Sofia CordobaDepartment of Radiation Oncology, Puerta de Hierro University Hospital, 28222 Majadahonda, Madrid, Spain.
Abel CordobaDepartment of Radiation Oncology, Oscar Lambret Comprehensive Cancer Center, 59000 Lille, France.
Beatriz GilDepartment of Radiation Oncology, Puerta de Hierro University Hospital, 28222 Majadahonda, Madrid, Spain.
Raquel BenllochDepartment of Radiation Oncology, Puerta de Hierro University Hospital, 28222 Majadahonda, Madrid, Spain.
Silvia RodriguezDepartment of Radiation Oncology, Clinica Benidorm Hospital, 30501 Benidorm, Alicante, Spain.
Dina Najjari-JamalDepartment of Radiation Oncology, Catalan Institut of Oncology, University of Barcelona, Hospitalet de Llobregat, 08908 Barcelona, Spain.
Sofía SantanaDepartment of Radiation Oncology, Puerta de Hierro University Hospital, 28222 Majadahonda, Madrid, Spain.
Lucie BressonDepartment of Surgical Oncology, Henin-Beaumont Polyclinic, 62110 Henin Beaumont, France.
Cristina de la FuenteDepartment of Radiation Oncology, Puerta de Hierro University Hospital, 28222 Majadahonda, Madrid, Spain.
Jesús RomeroDepartment of Radiation Oncology, Puerta de Hierro University Hospital, 28222 Majadahonda, Madrid, Spain.ORCID 0000-0001-8778-1388
Hospital Universitario Puerta de Hierro Majadahonda · ESCentre Oscar Lambret · FRHospital Clínica Benidorm · ESInstitut Català d'Oncologia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vulvar cancer is a relatively rare neoplasm. The essential treatment is surgery for the primary tumour. However, postoperative recurrence rates are high, even in early-stage disease when tumour-free surgical margins are achieved or in the absence of associated risk factors (lymph node metastases, deep stromal invasion or invasion of the lymphatic vascular space). Radiotherapy plays an important role in the treatment of vulvar cancer. Adjuvant treatment after surgery as well as primary treatment of locally advanced vulvar cancer (LAVC) is composed of two key radiotherapy treatment scenarios, external beam radiation therapy (EBRT) either combined or not combined with brachytherapy (BT). In a recurrence setting, where surgery is not an option, BT alone or in combination with EBRT can be used. Compared to EBRT, BT has the radiobiological potential to improve dose to the target volume, minimise the dose to organs at risk, and facilitate hypofractionated-accelerated treatment. This narrative review presents recent data on the role of BT in the treatment of primary and/or recurrent vulvar cancer, including radiobiological, clinical, and therapeutic aspects.

Indexed as

brachytherapyradiation therapyradiobiologyvulvar cancer

Identifiers

PMID38067285
PMCPMC10705127
OpenAlexW4389056358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.