Evidence map›Paper›PMID 38067257›Full record

ArticleCancers2023

Iris H C Miedema, Jessica E Wijngaarden, Johanna E E Pouw, Gerben J C Zwezerijnen, Hylke J Sebus, Egbert Smit, Adrianus J de Langen, Idris Bahce, Andrea Thiele, Daniëlle J Vugts and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. EJNMMI research · 2025
    Article
  7. [Immunotherapy advances · 2025
    Article
  8. Non-specific irreversibleEJNMMI research · 2024
    Article
  9. Review
  10. Advances and challenges in immunoPET methodology.Frontiers in nuclear medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Iris H C MiedemaDepartment of Medical Oncology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0002-7581-5277
Jessica E WijngaardenCancer Center Amsterdam, Imaging and Biomarkers, De Boelelaan 1118, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0003-1486-6246
Johanna E E PouwDepartment of Medical Oncology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0003-1358-1804
Gerben J C ZwezerijnenCancer Center Amsterdam, Imaging and Biomarkers, De Boelelaan 1118, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0002-9571-9362
Hylke J SebusDepartment of Medical Oncology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Egbert SmitDepartment of Pulmonary Diseases, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
Adrianus J de LangenDepartment of Thoracic Oncology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 21, 1066 CX Amsterdam, The Netherlands.
Idris BahceCancer Center Amsterdam, Imaging and Biomarkers, De Boelelaan 1118, 1081 HV Amsterdam, The Netherlands.
Andrea ThieleDepartment of Translational Medicine & Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397 Biberach, Germany.
Daniëlle J VugtsCancer Center Amsterdam, Imaging and Biomarkers, De Boelelaan 1118, 1081 HV Amsterdam, The Netherlands.
Ronald BoellaardCancer Center Amsterdam, Imaging and Biomarkers, De Boelelaan 1118, 1081 HV Amsterdam, The Netherlands.
Marc C HuismanCancer Center Amsterdam, Imaging and Biomarkers, De Boelelaan 1118, 1081 HV Amsterdam, The Netherlands.
C Willemien Menke-van der Houven van OordtDepartment of Medical Oncology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLBoehringer Ingelheim (Germany) · DELeiden University Medical Center · NLThe Netherlands Cancer Institute · NL

Funding

Innovative Medicines Initiative 831514
6 · The paper itself

Abstract

introduction

method

resultsAll mAbs, except ipilimumab, showed K

conclusionUsing Patlak analysis and the established ns-baseline values, evidence for target engagement in (lymphoid) organs for several immune checkpoint inhibitors could be demonstrated. A decrease in the K

Indexed as

89Zr-immuno-PETimmune checkpoint inhibitorstarget engagement

Identifiers

PMID38067257
PMCPMC10705667
OpenAlexW4388942438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.