Evidence map›Paper›PMID 38067233›Full record

ArticleCancers2023

NIR ICG-Enhanced Fluorescence: A Quantitative Evaluation of Bowel Microperfusion and Its Relation to Central Perfusion in Colorectal Surgery.

Norma Depalma, Stefano D'Ugo, Farshad Manoochehri, Annarita Libia, William Sergi, Tiziana R L Marchese, Stefania Forciniti, Loretta L Del Mercato, Prisco Piscitelli, Stefano Garritano and 3 more

Abstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  3. Observational
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Norma DepalmaDepartment of General Surgery, "Vito Fazzi" Hospital, Piazza Filippo Muratore 1, 73100 Lecce, Italy.ORCID 0000-0001-5451-2923
Stefano D'UgoDepartment of General Surgery, "Vito Fazzi" Hospital, Piazza Filippo Muratore 1, 73100 Lecce, Italy.
Farshad ManoochehriDepartment of General Surgery, "Vito Fazzi" Hospital, Piazza Filippo Muratore 1, 73100 Lecce, Italy.
Annarita LibiaDepartment of General Surgery, "Vito Fazzi" Hospital, Piazza Filippo Muratore 1, 73100 Lecce, Italy.
William SergiDepartment of General Surgery, "Vito Fazzi" Hospital, Piazza Filippo Muratore 1, 73100 Lecce, Italy.
Tiziana R L MarcheseDepartment of General Surgery, "Vito Fazzi" Hospital, Piazza Filippo Muratore 1, 73100 Lecce, Italy.
Stefania ForcinitiInstitute of Nanotechnology, National Research Council (CNR-NANOTEC), c/o Campus Ecotekne, Via Monteroni, 73100 Lecce, Italy.ORCID 0000-0001-6719-1591
Loretta L Del MercatoInstitute of Nanotechnology, National Research Council (CNR-NANOTEC), c/o Campus Ecotekne, Via Monteroni, 73100 Lecce, Italy.ORCID 0000-0001-9733-7088
Prisco PiscitelliDepartment of Experimental Medicine, University of Salento, 73100 Lecce, Italy.
Stefano GarritanoDepartment of General Surgery, "Vito Fazzi" Hospital, Piazza Filippo Muratore 1, 73100 Lecce, Italy.
Fabio CastellanaDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Piazza Umberto I, 70121 Bari, Italy.
Roberta ZupoDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Piazza Umberto I, 70121 Bari, Italy.ORCID 0000-0001-9885-1185
Marcello Giuseppe SpampinatoDepartment of General Surgery, "Vito Fazzi" Hospital, Piazza Filippo Muratore 1, 73100 Lecce, Italy.

Funding

European Research Council (ERC) contract number 759959the Associazione Italiana per la Ricerca contro il Cancro (AIRC) contract number 22902
6 · The paper itself

Abstract

backgroundTo date, no standardized protocols nor a quantitative assessment of the near-infrared fluorescence angiography with indocyanine green (NIR-ICG) are available. The aim of this study was to evaluate the timing of fluorescence as a reproducible parameter and its efficacy in predicting anastomotic leakage (AL) in colorectal surgery.

methodsA consecutive cohort of 108 patients undergoing minimally invasive elective procedures for colorectal cancer was prospectively enrolled. The difference between macro and microperfusion (ΔT) was obtained by calculating the timing of fluorescence at the level of iliac artery division and colonic wall, respectively.

resultsSubjects with a ΔT ≥ 15.5± 0.5 s had a higher tendency to develop an AL (

conclusionsThe analysis of the timing of fluorescence provides a quantitative, easy evaluation of tissue perfusion. A ΔT/HR interaction ≥832 may be used as a real-time parameter to guide surgical decision making in colorectal surgery.

Indexed as

anastomotic leakagecolorectal cancerminimally invasive colorectal surgeryNIR-ICG-enhanced fluorescence

Identifiers

PMID38067233
PMCPMC10705733

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.