Evidence map›Paper›PMID 38067231›Full record

ArticleCancers2023

CD4, CD20 and PD-L1 as Markers of Recurrence in Non-Muscle-Invasive Bladder Cancer.

Aleksandra Semeniuk-Wojtaś, Magdalena Modzelewska, Karolina Poddębniak-Strama, Sylwia Kołaczyńska, Arkadiusz Lubas, Barbara Górnicka, Anna Jakieła, Rafał Stec

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Aleksandra Semeniuk-WojtaśOncology Department, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0001-9421-6694
Magdalena ModzelewskaPathomorphology Department, Medical University of Warsaw, 02-091 Warsaw, Poland.
Karolina Poddębniak-StramaOncology Department, 4 Military Clinical Hospital with a Polyclinic, 53-114 Wroclaw, Poland.
Sylwia KołaczyńskaOncology Department, 4 Military Clinical Hospital with a Polyclinic, 53-114 Wroclaw, Poland.
Arkadiusz LubasDepartment of Internal Medicine, Nephrology and Dialysis, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.ORCID 0000-0002-3248-4615
Barbara GórnickaPathomorphology Department, Medical University of Warsaw, 02-091 Warsaw, Poland.
Anna JakiełaOncology Department, 4 Military Clinical Hospital with a Polyclinic, 53-114 Wroclaw, Poland.
Rafał StecOncology Department, Medical University of Warsaw, 02-091 Warsaw, Poland.
Medical University of Warsaw · PL1 Military Clinical Hospital with Outpatient Clinic · PL

Funding

Phizer PolskaSp z o.o. #68288599
6 · The paper itself

Abstract

introductionA tumor microenvironment plays an important role in bladder cancer development and in treatment response. PURPOSE: The aim of the study was to assess how the components of the microenvironment affect tumor recurrence and to find the potential biomarkers for immunotherapy in NMIBC.

methodsThe study group consisted of 55 patients with primary NMIBC. Immunohistochemistry was performed on sections of primary papillary urothelial carcinoma of the bladder. Cox proportional hazard multiple regression analysis was performed to characterize tumors with the highest probability of an unfavorable outcome.

resultsMultivariate analysis confirmed that the CD4 (

conclusionsThe evaluation of CD4

Indexed as

bladder cancerCD20CD4immune cellsNMIBCPD-L1tumor microenvironment

Identifiers

PMID38067231
PMCPMC10705362
OpenAlexW4388902076

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.