Evidence map›Paper›PMID 38067203›Full record

ReviewCancers2023

Unlocking New Avenues in Breast Cancer Treatment: The Synergy of Kinase Inhibitors and Immunotherapy.

María José Bravo, Antonio Manuel Burgos-Molina, Marilina García-Aranda, Maximino Redondo, Teresa Téllez

Abstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Advances in pyrazolo[1,5-RSC advances · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

María José BravoSurgery, Biochemistry and Immunology Department, School of Medicine, University of Malaga, 29010 Malaga, Spain.
Antonio Manuel Burgos-MolinaSurgery, Biochemistry and Immunology Department, School of Medicine, University of Malaga, 29010 Malaga, Spain.ORCID 0000-0001-5663-5134
Marilina García-ArandaSurgery, Biochemistry and Immunology Department, School of Medicine, University of Malaga, 29010 Malaga, Spain.ORCID 0000-0003-3759-4044
Maximino RedondoSurgery, Biochemistry and Immunology Department, School of Medicine, University of Malaga, 29010 Malaga, Spain.ORCID 0000-0001-5559-4246
Teresa TéllezSurgery, Biochemistry and Immunology Department, School of Medicine, University of Malaga, 29010 Malaga, Spain.ORCID 0000-0002-9935-5586

Funding

Consejería de Salud Junta de Andalucia PI 16/0298Malaga University UMA20-FEDERJA-161REDISSEC RD12/0001/0010 and RD16/0001/0006RICAPPS RD21/0016/0015
6 · The paper itself

Abstract

Cancer is one of the world's most significant health problems today. Currently, breast cancer has globally surpassed lung cancer as the most commonly diagnosed cancer in women. In 2020, an estimated 2,261,419 new cases were diagnosed in women worldwide. Therefore, there is a need to understand the processes that can help us better treat this disease. In recent years, research in the fight against cancer has often been based on two treatment modalities. One of them is the use of protein kinase inhibitors, which have been instrumental in the development of new therapeutic strategies. Another crucial route is the use of immunotherapy, which has been touted as a great promise for cancer treatment. Protein kinase alterations can interfere with the effectiveness of other treatments, such as immunotherapy. In this review, we will analyze the role played by protein kinase alterations in breast cancer and their possible impact on the effectiveness of the response to immunotherapy treatments.

Indexed as

antibody monoclonalbreast cancercombination therapiesimmunotherapyinhibitorprotein kinase

Identifiers

PMID38067203
PMCPMC10705185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.