Evidence map›Paper›PMID 38067156›Full record

ArticleCells2023

Life-Cycle-Dependent Toxicities of Mono- and Bifunctional Alkylating Agents in the 3R-Compliant Model Organism

Joanna Ruszkiewicz, Lisa Endig, Ebru Güver, Alexander Bürkle, Aswin Mangerich

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joanna RuszkiewiczMolecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.ORCID 0000-0003-1093-1362
Lisa EndigMolecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.
Ebru GüverMolecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.
Alexander BürkleMolecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.ORCID 0000-0003-1069-2656
Aswin MangerichMolecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.ORCID 0000-0001-9742-2338
University of Konstanz · DEUniversity of Potsdam · DE

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alkylating AgentsCaenorhabditis elegansAnimalsHumansLife Cycle StagesMustard GasNAD2-chloroethyl ethyl sulfideAlkylating AgentsMustard GasNADalkylating agentsC. eleganslife cycle toxicitiesmustardsNAD+neurotoxicity

Identifiers

PMID38067156
PMCPMC10705807
OpenAlexW4389143876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.