Evidence map›Paper›PMID 38067144›Full record

ArticleCells2023

Sertoli Cell-Specific Activation of Transforming Growth Factor Beta Receptor 1 Leads to Testicular Granulosa Cell Tumor Formation.

Xin Fang, Linfeng Nie, Satwikreddy Putluri, Nan Ni, Laurent Bartholin, Qinglei Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Sertoli cells as a hub in testicular development and male reproductive.Frontiers in cell and developmental biology · 2025
    Review
  2. Functional Study of PTSMAD4 in the Spermatogenesis of the Swimming CrabInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Xin FangDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77843, USA.
Linfeng NieDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77843, USA.
Satwikreddy PutluriDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77843, USA.
Nan NiDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77843, USA.
Laurent BartholinINSERM U1052, CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, Université Lyon 1, F-69000 Lyon, France.
Qinglei LiDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77843, USA.
Texas A&M University · USInserm · FR

Funding

A novel mouse model of testicular granulosa cell tumorsR03CA235001 · NCI · TEXAS A&M AGRILIFE RESEARCH · PI LI, QINGLEI · 2020 to 2021
$146k
NCI NIH HHS R03 CA235001NCI NIH HHS R03CA235001
6 · The paper itself

Abstract

The transforming growth factor β (TGFβ) superfamily, consisting of protein ligands, receptors, and intracellular SMAD transducers, regulates fundamental biological processes and cancer development. Our previous study has shown that sustained activation of TGFβ receptor 1 (TGFBR1) driven by anti-Mullerian hormone receptor type 2 (

Indexed as

Granulosa Cell TumorOvarian NeoplasmsTesticular NeoplasmsAnimalsAnti-Mullerian HormoneFemaleHumansMaleMiceNeoplasms, Germ Cell and EmbryonalReceptors, Transforming Growth Factor betaReceptor, Transforming Growth Factor-beta Type ISertoli CellsTransforming Growth Factor betaAnti-Mullerian HormoneReceptors, Transforming Growth Factor betaReceptor, Transforming Growth Factor-beta Type ITransforming Growth Factor betaSertoli celltesticular granulosa cell tumorTGFBR1transforming growth factor beta

Identifiers

PMID38067144
PMCPMC10706251
OpenAlexW4389036016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.