Evidence map›Paper›PMID 38067105›Full record

ArticleCells2023

Inward Operation of Sodium-Bicarbonate Cotransporter 1 Promotes Astrocytic Na

Katharina Everaerts, Pawan Thapaliya, Nils Pape, Simone Durry, Sara Eitelmann, Eleni Roussa, Ghanim Ullah, Christine R Rose

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. A dangerous liaison: Spreading depolarization and tissue acidification in cerebral ischemia.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Review
  7. Article
  8. Review
  9. Deletion of Slc9a1 in Cx3cr1Journal of neuroinflammation · 2024
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Katharina EveraertsInstitute of Neurobiology, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
Pawan ThapaliyaDepartment of Physics, University of South Florida, Tampa, FL 33620, USA.
Nils PapeInstitute of Neurobiology, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
Simone DurryInstitute of Neurobiology, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
Sara EitelmannInstitute of Neurobiology, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.ORCID 0000-0001-6827-7004
Eleni RoussaInstitute of Anatomy and Cell Biology, Department of Molecular Embryology, Faculty of Medicine, Albert-Ludwigs-Universität Freiburg, Albertstrasse 17, D-79104 Freiburg, Germany.ORCID 0000-0002-0495-1597
Ghanim UllahDepartment of Physics, University of South Florida, Tampa, FL 33620, USA.ORCID 0000-0002-3716-8742
Christine R RoseInstitute of Neurobiology, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.ORCID 0000-0002-9684-3592
Heinrich Heine University Düsseldorf · DEUniversity of South Florida · USUniversity of Freiburg · DE

Funding

CRCNS US-German Research Proposal: Quantitative and Computational Dissection of Glutamatergic Crosstalk at Tripartite SynapsesR01NS130916 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI Ghanim Ullah · 2023 to 2026
$487k
NIH HHS R01NS130916NINDS NIH HHS R01 NS130916
6 · The paper itself

Abstract

Ischemic conditions cause an increase in the sodium concentration of astrocytes, driving the breakdown of ionic homeostasis and exacerbating cellular damage. Astrocytes express high levels of the electrogenic sodium-bicarbonate cotransporter1 (NBCe1), which couples intracellular Na

Indexed as

AcidosisNeocortexAdenosine TriphosphateAnimalsAstrocytesIonsMiceMice, KnockoutSodiumSodium-Bicarbonate SymportersAdenosine TriphosphateIonsSodiumSodium-Bicarbonate SymportersastrocyteATPexcitotoxicityimagingischemiamodelingneocortexpHsodium

Identifiers

PMID38067105
PMCPMC10705779
OpenAlexW4388866702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.