Evidence map›Paper›PMID 38066798›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Role of Clinical Risk Factors and B-Type Natriuretic Peptide in Assessing the Risk of Asymptomatic Cardiotoxicity in Breast Cancer Patients in Kazakhstan.

Zhenisgul Tlegenova, Saule Balmagambetova, Bekbolat Zholdin, Gulnara Kurmanalina, Iliada Talipova, Arip Koyshybaev, Gulmira Sultanbekova, Mira Baspayeva, Saule Madinova, Kulparshan Kubenova and 2 more

Abstract read
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In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhenisgul TlegenovaDepartment of Internal Diseases-2, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Saule BalmagambetovaDepartment of Oncology, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Bekbolat ZholdinDepartment of Internal Diseases-2, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Gulnara KurmanalinaDepartment of Internal Diseases-2, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Iliada TalipovaDepartment of Internal Diseases-2, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Arip KoyshybaevDepartment of Oncology, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Gulmira SultanbekovaDepartment of Internal Diseases-2, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Mira BaspayevaChemotherapy Division at University Medical Center, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Saule MadinovaChemotherapy Division at University Medical Center, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Kulparshan KubenovaClinical Laboratory at University Medical Center, West Kazakhstan Marat Ospanov Medical University, Aktobe 030017, Kazakhstan.
Aiganym AmanovaDepartment of Internal Diseases-2, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.ORCID 0009-0001-9787-7583
Amin TamadonPercia Vista R&D Co., Shiraz, Iran.

Funding

the Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan IRN AP09259524
6 · The paper itself

Abstract

The asymptomatic progression of chemotherapy-induced cardiotoxicity poses a significant risk to breast cancer patients. In the present single-center cohort study, a predictive model for evaluating the risk of cardiotoxicity during or by the end of chemotherapy was designed. The risk-prediction nomogram was delineated and assessed. In total, 34 patients out of 120 developed asymptomatic cardiotoxicity (28.3%). Of six explored biomarkers, only B-type natriuretic peptide showed a reliable pattern of incremental increase, revealing statistical significance between cardiotoxicity "+" and "-" groups by visit 4 or by the 9th month of monitoring (

Indexed as

biomarkersbreast cancerB-type natriuretic peptidecardiotoxicitychemotherapyKazakhstanpredictive modelsrisk factors

Identifiers

PMID38066798
PMCPMC10706779

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.