Evidence map›Paper›PMID 38066760›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Allergy Test Dosage of Fluorescein Detects Diabetic Retinopathy Changes in Fundus Fluorescein Angiography.

Jian-Feng Yang, Yun Wang, Lingling Zhou, Shaoying Tan, Zhanchi Hu, Tsz Kin Ng, Ling-Ping Cen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Correlation between macular perfusion status and visual acuity in retinal vein occlusion.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jian-Feng YangJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou 515041, China.
Yun WangJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou 515041, China.
Lingling ZhouJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou 515041, China.
Shaoying TanJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou 515041, China.ORCID 0000-0001-9997-7396
Zhanchi HuJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou 515041, China.
Tsz Kin NgJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou 515041, China.ORCID 0000-0001-7863-7229
Ling-Ping CenJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou 515041, China.
Chinese University of Hong Kong · HKHong Kong Polytechnic University · HK

Funding

an internal grant from the Joint Shantou International Eye Center of The Shantou University and The Chinese University of Hong Kong 18-008Natural Science Foundation of Guangdong Province, China 2020A1515011413the National Natural Science Foundation of China 81570849
6 · The paper itself

Abstract

backgroundThe aims of this study were to evaluate the feasibility of allergy test dosage of fluorescein sodium (1%) for Diabetic Retinopathy (DR) detection in Fundus Fluorescein Angiography (FFA) examination as compared to the regular dosage (20%).

methodsTotally 77 eyes from 42 DR patients were included in this prospective study. Capillary non-perfusion area, neovascularization, diabetic macular edema and microaneurysms were measured by FFA and compared at 1, 5 and 15 min after intravenous injection of 1% or 20% fluorescein sodium.

resultsThere was no statistically significant difference in the proportions of capillary non-perfusion area and diabetic macular edema as well as the amount of neovascularization between the 1% and 20% fluorescein sodium groups. Yet, the 1% group had a significantly a smaller number of microaneurysms than the 20% group at 1 min (

conclusionsThis study demonstrated that 1% fluorescein sodium could detect the changes of DR comparably to the regular dosage.

Indexed as

diabetic retinopathyfluorescein sodium allergy testfundus fluorescein angiography

Identifiers

PMID38066760
PMCPMC10706110
OpenAlexW4388939415

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.