Evidence map›Paper›PMID 38066754›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Unpredictable Metastasis in the Head and Neck Region: A Diagnostic Immunohistochemical Challenge.

Raluca-Maria Closca, Adrian Nicoara, Marina Rakitovan, Ion Cristian Mot, Flavia Baderca

Open access · goldAbstract readCase Reports
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Renal clear cell carcinoma with bilateral parotid and orbital metastases - case report.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Raluca-Maria CloscaDepartment of Microscopic Morphology, University of Medicine and Pharmacy "Victor Babes", 300041 Timisoara, Romania.ORCID 0009-0001-1397-1864
Adrian NicoaraOro-Maxillo-Facial Surgery Clinic, Emergency City Hospital, 300062 Timisoara, Romania.
Marina RakitovanOro-Maxillo-Facial Surgery Clinic, Emergency City Hospital, 300062 Timisoara, Romania.
Ion Cristian MotOtorhinolaryngology Clinic, Emergency City Hospital, 300254 Timisoara, Romania.
Flavia BadercaDepartment of Microscopic Morphology, University of Medicine and Pharmacy "Victor Babes", 300041 Timisoara, Romania.ORCID 0000-0002-5755-179X
Clinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastatic disease is a complex and sequential process that involves the migration of tumor cells from the primary site to distant areas. This metastatic pathway is not always predictable. Therefore, this paper presents three rare cases of unusual metastases, due to their primary site: two metastases of a clear cell renal cell carcinoma, one gingival, and one nasal, as well as a mandibular metastasis of a hepatocellular carcinoma. In all cases, an incisional biopsy was performed in order to find out the diagnosis. After microscopical examination of morphological Hematoxylin and Eosin-stained slides, for all cases, immunohistochemical reactions were performed to support the primary tumor site. Two cases had a previous histopathological diagnosis of a primary tumor, while for the third case, the metastatic lesion represented the first manifestation of the neoplastic disease, with an unfavorable prognosis.

Indexed as

head and neckhepatocellular carcinomaimmunohistochemistryrenal clear cell carcinomaunusual metastases

Identifiers

PMID38066754
PMCPMC10706832
OpenAlexW4388944067

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.