Synthesis of pyrano-pyrimidines: recent advances in catalysis by magnetically recoverable nanocatalysts.

The widespread use of catalysts in chemistry in the current century, especially in multicomponent reactions, has led researchers to design catalysts with high catalytic power and which can be recycled. In recent years, most scientists and researchers of chemical science have become interested in magnetic nanocatalysts and used them to perform chemical reactions. Due to the magnetic property of this nanocatalyst, it can be separated and collected from the reaction mixture by a magnet after the reaction is complete and reused. Pyrano-pyrimidines are a group of heterocyclic compounds and important pharmaceutical compounds. Pyrano-pyrimidine derivatives are of great interest due to the wide role they play in biological activities. During the past years, various methods for the synthesis of pyrano-pyrimidines based on the use of magnetic nanocatalysts have been reported. In this review article, for the first time, we would like to focus on the reported non-magnetic materials as magnetically recoverable nanocatalysts for the synthesis of pyrano-pyrimidine derivatives. Considering the wonderful features of magnetic nanocatalysts such as simple separation and preparation, high catalytic activity and stability, we expect more articles on the synthesis of heterocycles using this type of catalyst to be published in the near future.