Evidence map›Paper›PMID 38066221›Full record

Observational studyJournal of community health2024

Vaccine Effectiveness Against SARS-CoV-2 Related Hospitalizations in People who had Experienced Homelessness or Incarceration - Findings from the Minnesota EHR Consortium.

Malini B DeSilva, Gregory Knowlton, Nayanjot K Rai, Peter Bodurtha, Inih Essien, John Riddles, Lemlem Mehari, Miriam Muscoplat, Ruth Lynfield, Elizabeth Ak Rowley and 10 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Journal of community health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
  3. Privacy preserving record linkage for public health action: opportunities and challenges.Journal of the American Medical Informatics Association : JAMIA · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 1 country.

Malini B DeSilvaHealth Partners Institute, 8170 33rd Ave South, Mail stop 21112R, Bloomington, MN, 55440-1524, USA. malini.b.desilva@healthpartners.com.ORCID 0000-0003-3705-1672
Gregory KnowltonHealth Partners Institute, 8170 33rd Ave South, Mail stop 21112R, Bloomington, MN, 55440-1524, USA.
Nayanjot K RaiDivision of Nephrology & Hypertension, University of Minnesota, Minneapolis, MN, USA.
Peter BodurthaHealth, Homelessness and Criminal Justice Lab, Hennepin Healthcare Research Institute, Minneapolis, MN, USA.
Inih EssienHealth Partners Institute, 8170 33rd Ave South, Mail stop 21112R, Bloomington, MN, 55440-1524, USA.
John RiddlesWestat, Rockville, MD, USA.
Lemlem MehariWestat, Rockville, MD, USA.
Miriam MuscoplatDivision of Infectious Disease, Epidemiology, Prevention, and Control, Department of Health, St Paul, Minnesota, MN, USA.
Ruth LynfieldMinnesota Department of Health, St Paul, MN, USA.
Elizabeth Ak RowleyWestat, Rockville, MD, USA.
Alanna M ChamberlainMayo Clinic, Rochester, MN, USA.
Palak PatelCenters for Disease Control and Prevention COVID-19 Response Team, Atlanta, GA, USA.
Alexandria HughesWestat, Rockville, MD, USA.
Monica DickersonCenters for Disease Control and Prevention COVID-19 Response Team, Atlanta, GA, USA.
Mark G ThompsonCenters for Disease Control and Prevention COVID-19 Response Team, Atlanta, GA, USA.
Eric P GriggsCenters for Disease Control and Prevention COVID-19 Response Team, Atlanta, GA, USA.
Mark TenfordeCenters for Disease Control and Prevention COVID-19 Response Team, Atlanta, GA, USA.
Tyler Na WinkelmanHealth, Homelessness and Criminal Justice Lab, Hennepin Healthcare Research Institute, Minneapolis, MN, USA.
Gabriela Vazquez BenitezHealth Partners Institute, 8170 33rd Ave South, Mail stop 21112R, Bloomington, MN, 55440-1524, USA.
Paul E DrawzDivision of Nephrology & Hypertension, University of Minnesota, Minneapolis, MN, USA.
Centers for Disease Control and Prevention · USHealthPartners · USWestat (United States) · USHennepin Healthcare Research Institute · USMinnesota Department of Health · USUniversity of Minnesota · USMayo Clinic in Arizona · US

Funding

CDC HHS 75D30120C07986-6765-00-SA002
6 · The paper itself

Abstract

COVID-19 disproportionately affects people experiencing homelessness or incarceration. While homelessness or incarceration alone may not impact vaccine effectiveness, medical comorbidities along with social conditions associated with homelessness or incarceration may impact estimated vaccine effectiveness. COVID-19 vaccines reduce rates of hospitalization and death; vaccine effectiveness (VE) against severe outcomes in people experiencing homelessness or incarceration is unknown. We conducted a retrospective, observational cohort study evaluating COVID-19 vaccine VE against SARS-CoV-2 related hospitalization (positive SARS-CoV-2 molecular test same week or within 3 weeks prior to hospital admission) among patients who had experienced homelessness or incarceration. We utilized data from 8 health systems in the Minnesota Electronic Health Record Consortium linked to data from Minnesota's immunization information system, Homeless Management Information System, and Department of Corrections. We included patients 18 years and older with a history of experiencing homelessness or incarceration. VE and 95% Confidence Intervals (CI) against SARS-CoV-2 hospitalization were estimated for primary series and one booster dose from Cox proportional hazard models as 100*(1-Hazard Ratio) during August 26, 2021, through October 8, 2022 adjusting for patient age, sex, comorbid medical conditions, and race/ethnicity. We included 80,051 individuals who had experienced homelessness or incarceration. Adjusted VE was 52% (95% CI, 41-60%) among those 22 weeks or more since their primary series, 66% (95% CI, 53-75%) among those less than 22 weeks since their primary series, and 69% (95% CI: 60-76%) among those with one booster. VE estimates were consistently lower during the Omicron predominance period compared with the combined Omicron and Delta periods. Despite higher exposure risk, COVID-19 vaccines provided good effectiveness against SARS-CoV-2 related hospitalizations in persons who have experienced homelessness or incarceration.

Indexed as

COVID-19Ill-Housed PersonsCOVID-19 VaccinesHospitalizationHumansIncarcerationMinnesotaRetrospective StudiesSARS-CoV-2Vaccine EfficacyCOVID-19 VaccinesCOVID-19COVID-19 VaccinesHomelessnessMinnesota

Identifiers

PMID38066221
PMCPMC10981627
OpenAlexW4389472841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.