Evidence map›Paper›PMID 38065980›Full record

SynthesisScientific reports2023

Circulating miRNA profiles in COVID-19 patients and meta-analysis: implications for disease progression and prognosis.

Liangliang Gao, Espoir M Kyubwa, Mark A Starbird, Jesus Diaz de Leon, Michelle Nguyen, Claude J Rogers, Naresh Menon

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Liangliang Gao *ChromoLogic, LLC, Monrovia, CA, USA.ORCID 0000-0002-3864-0631
Espoir M Kyubwa *ChromoLogic, LLC, Monrovia, CA, USA.
Mark A StarbirdChromoLogic, LLC, Monrovia, CA, USA.
Jesus Diaz de LeonChromoLogic, LLC, Monrovia, CA, USA.
Michelle NguyenChromoLogic, LLC, Monrovia, CA, USA.
Claude J RogersChromoLogic, LLC, Monrovia, CA, USA. crogers@chromologic.com.
Naresh MenonChromoLogic, LLC, Monrovia, CA, USA. nmenon@chromologic.com.ORCID 0000-0003-1359-6280
ChromoLogic (United States) · US

Funding

NIAID NIH HHS HHSN272201700012CNIH HHS HHSN272201700012C
6 · The paper itself

Abstract

We compared circulating miRNA profiles of hospitalized COVID-positive patients (n = 104), 27 with acute respiratory distress syndrome (ARDS) and age- and sex-matched healthy controls (n = 18) to identify miRNA signatures associated with COVID and COVID-induced ARDS. Meta-analysis incorporating data from published studies and our data was performed to identify a set of differentially expressed miRNAs in (1) COVID-positive patients versus healthy controls as well as (2) severe (ARDS

Indexed as

Circulating MicroRNACOVID-19Respiratory Distress SyndromeDisease ProgressionFemaleHumansMalePrognosisCirculating MicroRNA

Identifiers

PMID38065980
PMCPMC10709343
OpenAlexW4389482248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.