Evidence map›Paper›PMID 38065979›Full record

ArticleSchizophrenia (Heidelberg, Germany)2023

Effects of independent versus dependent stressful life events on major symptom domains of schizophrenia.

Yizhou Ma, Joshua Chiappelli, Mark D Kvarta, Heather Bruce, Andrew van der Vaart, Eric L Goldwaser, Xiaoming Du, Hemalatha Sampath, Samantha Lightner, Jane Endres and 6 more

Abstract read
In one paragraph

Article in Schizophrenia (Heidelberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yizhou MaMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA. yizhou.ma@som.umaryland.edu.ORCID http://orcid.org/0000-0002-2775-5660
Joshua ChiappelliMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-6121-7439
Mark D KvartaMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-1093-1648
Heather BruceMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-5630-3041
Andrew van der VaartMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Eric L GoldwaserDepartment of Psychiatry, Weill Cornell Medical College/New York-Presbyterian Hospital, New York, NY, USA.
Xiaoming DuMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-7206-5282
Hemalatha SampathMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Samantha LightnerMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Jane EndresMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Akram YusufMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Alexa YuenMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Samantha NarvaezMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Danny Campos-SaraviaMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Peter KochunovMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
L Elliot HongMaryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.

Funding

SOLAR-Eclipse Computational Tools for Imaging GeneticsR01EB015611 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOCHUNOV, PETER V. · 2012 to 2024
$5.0M
Amish Connectome Project on Mental IllnessU01MH108148 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT, KOCHUNOV, PETER V. · 2015 to 2018
$4.3M
Towards Multisystem-Brain Successful Aging in Schizophrenia SpectrumR01MH116948 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HONG, L ELLIOT ELLIOT · 2018 to 2022
$3.7M
Lifespan Vascular Biology on White MatterRF1NS114628 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT, KOCHUNOV, PETER V. · 2020 to 2020
$3.1M
The Vascular Axis in Schizophrenia Brain-Body AgingR01MH133812 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI L Elliot Elliot Hong · 2024 to 2026
$2.2M
A global alliance to unlock brain mechanisms influencing suicidal behaviors through the ENIGMA ConsortiumR01MH117601 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JAHANSHAD, NEDA, SCHMAAL, LIANNE · 2018 to 2021
$1.5M
Redefine Trans-Neuropsychiatric Disorder Brain Patterns through Big-Data and Machine LearningRF1MH123163 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI KOCHUNOV, PETER V., THOMPSON, PAUL M · 2021 to 2021
$1.2M
The Role of Stress-Immune-Connectome Disruption in Mechanisms of Chinese Early Schizophrenia SpectrumR01MH112180 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT · 2017 to 2021
$1.0M
Lifespan Vascular Biology on White MatterR01NS114628 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI HONG, L ELLIOT ELLIOT, KOCHUNOV, PETER V. · 2024 to 2024
$770k
Hybrid GPU/CPU Computing Resource to Support Connectomic and GenomicsS10OD023696 · OD · UNIVERSITY OF MARYLAND BALTIMORE · PI KOCHUNOV, PETER V. · 2018 to 2018
$593k
NIBIB NIH HHS R01 EB015611NIH HHS S10 OD023696NIMH NIH HHS R01 MH112180NIMH NIH HHS R01 MH116948NIMH NIH HHS R01 MH117601NIMH NIH HHS R01 MH133812NIMH NIH HHS RF1 MH123163NIMH NIH HHS U01 MH108148NINDS NIH HHS R01 NS114628NINDS NIH HHS RF1 NS114628
6 · The paper itself

Abstract

We evaluated two models to link stressful life events (SLEs) with the psychopathology of schizophrenia spectrum disorders (SSD). We separated SLEs into independent (iSLEs, unlikely influenced by one's behavior) and dependent (dSLEs, likely influenced by one's behavior). Stress-diathesis and stress generation models were evaluated for the relationship between total, i- and d- SLEs and the severity of positive, negative, and depressive symptoms in participants with SSD. Participants with SSD (n = 286; 196 males; age = 37.5 ± 13.5 years) and community controls (n = 121; 83 males; 35.4 ± 13.9 years) completed self-report of lifetime negative total, i- and d- SLEs. Participants with SSD reported a significantly higher number of total SLEs compared to controls (B = 1.11, p = 6.4 × 10

Identifiers

PMID38065979
PMCPMC10709301

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.