ReviewProgress in nuclear magnetic resonance spectroscopy
Micron-scale magnetic resonance imaging based on low temperatures and dynamic nuclear polarization.
Review in Progress in nuclear magnetic resonance spectroscopy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Optical widefield nuclear magnetic resonance microscopy.Nature communications · 2025Article
- Proton-detected 3D (1)H/(13)C/(1)H correlation experiment for structural analysis in rigid solids under ultrafast-MAS above 60 kHz.The Journal of chemical physics · 2015Article
- Spin diffusion driven by R-symmetry sequences: applications to homonuclear correlation spectroscopy in MAS NMR of biological and organic solids.Journal of the American Chemical Society · 2011Article
- Determination of relative tensor orientations by γ-encoded chemical shift anisotropy/heteronuclear dipolar coupling 3D NMR spectroscopy in biological solids.Physical chemistry chemical physics : PCCP · 2010Article
- The Alzheimer's beta amyloid (Abeta1-39) monomer in an implicit solvent.The Journal of chemical physics · 2008Article
- Solid-state NMR as a probe of amyloid structure.Protein and peptide letters · 2006Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Extension of magnetic resonance imaging (MRI) techniques to the single micron scale has been the goal of research in multiple laboratories over several decades. It has proven difficult to achieve isotropic spatial resolution better than 3.0 μm in inductively-detected MRI near 300 K, even with well-behaved test samples, microcoils, and optimized MRI pulse sequences. This article examines the factors that limit spatial resolution in MRI, especially the inherently low signal-to-noise ratio of nuclear magnetic resonance (NMR), and explains how these limiting factors can be overcome in principle, by acquiring MRI data at low temperatures and using dynamic nuclear polarization (DNP) to enhance signal amplitudes. Recent efforts directed at micron-scale MRI enabled by low-temperature DNP, culminating in images with 1.7 μm isotropic resolution obtained at 5 K, are reviewed. The article concludes with a discussion of areas in which further developments are likely to lead to further improvements in resolution, eventually to 1.0 μm or better.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.