Evidence map›Paper›PMID 38064636›Full record

ArticleJMIR formative research2023

A Biobanking System for Diagnostic Images: Architecture Development, COVID-19-Related Use Cases, and Performance Evaluation.

Giuseppina Esposito, Ciro Allarà, Marco Randon, Marco Aiello, Marco Salvatore, Giuseppe Aceto, Antonio Pescapè

Open access · goldAbstract read
In one paragraph

Article in JMIR formative research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Giuseppina EspositoBio Check Up Srl, Naples, Italy.ORCID https://orcid.org/0000-0003-2811-4678
Ciro AllaràBio Check Up Srl, Naples, Italy.ORCID https://orcid.org/0000-0002-8567-0104
Marco RandonBio Check Up Srl, Naples, Italy.ORCID https://orcid.org/0000-0002-7728-7842
Marco AielloIRCCS SYNLAB SDN, Naples, Italy.ORCID https://orcid.org/0000-0002-3676-0664
Marco SalvatoreIRCCS SYNLAB SDN, Naples, Italy.ORCID https://orcid.org/0000-0001-9734-7702
Giuseppe AcetoDepartment of Electrical Engineering and Information Technology, University of Naples Federico II, Naples, Italy.ORCID https://orcid.org/0000-0002-4445-6259
Antonio PescapèDepartment of Electrical Engineering and Information Technology, University of Naples Federico II, Naples, Italy.ORCID https://orcid.org/0000-0002-0221-7444
Krankenhaus Bruneck · ITUniversity of Naples Federico II · ITFree University of Bozen-Bolzano · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystems capable of automating and enhancing the management of research and clinical data represent a significant contribution of information and communication technologies to health care. A recent advancement is the development of imaging biobanks, which are now enabling the collection and storage of diagnostic images, clinical reports, and demographic data to allow researchers identify associations between lifestyle and genetic factors and imaging-derived phenotypes.

objectiveThe aim of this study was to design and evaluate the system performance of a network for an operating biobank of diagnostic images, the Bio Check Up Srl (BCU) Imaging Biobank, based on the Extensible Neuroimaging Archive Toolkit open-source platform.

methodsThree usage cases were designed focusing on evaluation of the memory and computing consumption during imaging collections upload and during interactions between two kinds of users (researchers and radiologists) who inspect chest computed tomography scans of a COVID-19 cohort. The experiments considered three network setups: (1) a local area network, (2) virtual private network, and (3) wide area network. The experimental setup recorded the activity of a human user interacting with the biobank system, which was continuously replayed multiple times. Several metrics were extracted from network traffic traces and server logs captured during the activity replay.

resultsRegarding the diagnostic data transfer, two types of containers were considered: the Web and the Database containers. The Web appeared to be the more memory-hungry container with a higher computational load (average 2.7 GB of RAM) compared to that of the database. With respect to user access, both users demonstrated the same network performance level, although higher resource consumption was registered for two different actions: DOWNLOAD & LOGOUT (100%) for the researcher and OPEN VIEWER (20%-50%) for the radiologist.

conclusionsThis analysis shows that the current setup of BCU Imaging Biobank is well provisioned for satisfying the planned number of concurrent users. More importantly, this study further highlights and quantifies the resource demands of specific user actions, providing a guideline for planning, setting up, and using an image biobanking system.

Indexed as

biobankCOVID-19diagnosticseHealthnetwork performance

Identifiers

PMID38064636
PMCPMC10760513
OpenAlexW4389495561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.