Evidence map›Paper›PMID 38064553›Full record

ArticleScience advances2023

Eukaryotic Kv channel Shaker inactivates through selectivity filter dilation rather than collapse.

Robyn Stix, Xiao-Feng Tan, Chanhyung Bae, Ana I Fernández-Mariño, Kenton J Swartz, José D Faraldo-Gómez

Abstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Electric field-induced pore constriction in the human KProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Structure of the human TWIK-2 potassium channel and its inhibition by pimozide.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Dilation of ion selectivity filters in cation channels.Trends in biochemical sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robyn StixTheoretical Molecular Biophysics Laboratory, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0003-2128-7875
Xiao-Feng TanMolecular Physiology and Biophysics Section, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0001-9327-2424
Chanhyung BaeMolecular Physiology and Biophysics Section, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0003-3407-2857
Ana I Fernández-MariñoMolecular Physiology and Biophysics Section, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-6995-4529
Kenton J SwartzMolecular Physiology and Biophysics Section, Porter Neuroscience Research Center, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0003-3419-0765
José D Faraldo-GómezTheoretical Molecular Biophysics Laboratory, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0001-7224-7676

Funding

PROBING THE STRUCTURE AND FUNCTION OF POTASSIUM AND CALCIUM CHANNELSZ01NS002945 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI SWARTZ, KENTON J · 1997 to 2008
$1.9M
Intramural NIH HHS Z01 NS002945
6 · The paper itself

Abstract

Eukaryotic voltage-gated K

Indexed as

Ion Channel GatingPotassium Channels, Voltage-GatedCryoelectron MicroscopyDilatationPotassium Channels, Voltage-Gated

Identifiers

PMID38064553
PMCPMC10708196

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.