Evidence map›Paper›PMID 38064429›Full record

ArticleEnvironmental science & technology2023

Perfluorooctanesulfonic Acid and Perfluorooctanoic Acid Promote Migration of Three-Dimensional Colorectal Cancer Spheroids.

Jie Zheng, Boshi Sun, Domenica Berardi, Lingeng Lu, Hong Yan, Shujian Zheng, Oladimeji Aladelokun, Yangzhouyun Xie, Yujun Cai, Krystal J Godri Pollitt and 2 more

Open access · greenAbstract read
In one paragraph

Article in Environmental science & technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Jie ZhengDepartment of Environmental Health Sciences, Yale School of Public Health, Yale University, New Haven, Connecticut 06510, United States.ORCID 0000-0001-7123-7353
Boshi SunDivision of Surgical Oncology, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06510, United States.
Domenica BerardiDepartment of Environmental Health Sciences, Yale School of Public Health, Yale University, New Haven, Connecticut 06510, United States.
Lingeng LuDepartment of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, New Haven, Connecticut 06510, United States.
Hong YanDepartment of Environmental Health Sciences, Yale School of Public Health, Yale University, New Haven, Connecticut 06510, United States.
Shujian ZhengJackson Laboratory for Genomic Medicine, Farmington, Connecticut 06032, United States.
Oladimeji AladelokunDepartment of Environmental Health Sciences, Yale School of Public Health, Yale University, New Haven, Connecticut 06510, United States.
Yangzhouyun XieDivision of Vascular Surgery and Endovascular Therapy, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06510, United States.
Yujun CaiDivision of Vascular Surgery and Endovascular Therapy, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06510, United States.
Krystal J Godri PollittDepartment of Environmental Health Sciences, Yale School of Public Health, Yale University, New Haven, Connecticut 06510, United States.ORCID 0000-0001-7332-2228
Sajid A KhanDivision of Surgical Oncology, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06510, United States.
Caroline H JohnsonDepartment of Environmental Health Sciences, Yale School of Public Health, Yale University, New Haven, Connecticut 06510, United States.
Yale University · USHarbin Medical University · CNJackson Laboratory · US

Funding

The Yale Cancer Prevention and Control Training ProgramT32CA250803 · NCI · YALE UNIVERSITY · PI Melinda L Irwin, Xiaomei Ma · 2020 to 2026
$2.3M
NCI NIH HHS T32 CA250803
6 · The paper itself

Abstract

Perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) are persistent environmental contaminants that are of increasing public concern worldwide. However, their relationship with colorectal cancer (CRC) is poorly understood. This study aims to comprehensively investigate the effect of PFOS and PFOA on the development and progression of CRC

Indexed as

Alkanesulfonic AcidsColorectal NeoplasmsFluorocarbonsCaprylatesHumansProto-Oncogene Proteins p21(ras)Alkanesulfonic AcidsCaprylatesFluorocarbonsperfluorooctane sulfonic acidperfluorooctanoic acidProto-Oncogene Proteins p21(ras)Colorectal CancerEMTGlobal metabolomicsMigrationPFOAPFOS

Identifiers

PMID38064429
PMCPMC12903201
OpenAlexW4389475351

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.