Evidence map›Paper›PMID 38064420›Full record

ArticlePLOS global public health2023

Using electronic medical records to understand the impact of SARS-CoV-2 lockdown measures on maternal and neonatal outcomes in Kampala, Uganda.

Joseph Ouma, Lauren Hookham, Lorna Aol Akera, Gordon Rukundo, Mary Kyohere, Ayoub Kakande, Racheal Nakyesige, Philippa Musoke, Kirsty Le Doare

Open access · goldAbstract read
In one paragraph

Article in PLOS global public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Joseph OumaMakerere University Johns Hopkins University Research Collaboration, Kampala, Uganda.ORCID https://orcid.org/0000-0001-5249-7440
Lauren HookhamSt. George's University of London, London, United Kingdom.ORCID https://orcid.org/0000-0001-9703-655X
Lorna Aol AkeraMakerere University Johns Hopkins University Research Collaboration, Kampala, Uganda.ORCID https://orcid.org/0000-0001-6796-1904
Gordon RukundoMakerere University Johns Hopkins University Research Collaboration, Kampala, Uganda.ORCID https://orcid.org/0000-0002-2622-5254
Mary KyohereMakerere University Johns Hopkins University Research Collaboration, Kampala, Uganda.
Ayoub KakandeMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.ORCID https://orcid.org/0000-0002-0243-5601
Racheal NakyesigeMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.ORCID https://orcid.org/0000-0002-1061-1599
Philippa MusokeMakerere University Johns Hopkins University Research Collaboration, Kampala, Uganda.
Kirsty Le DoareMakerere University Johns Hopkins University Research Collaboration, Kampala, Uganda.
MUJHU Research Collaboration · UGSt George's, University of London · GBUganda Virus Research Institute · UG

Funding

Addressing the Research Capacity Gap in Global Child and Adolescent Health Disparities Utilizing Implementation and Data Sciences among Vulnerable Populations in Resource-limited Settings (ACHIEVE)D43TW012275 · FIC · WASHINGTON UNIVERSITY · PI Theresa Stichick Betancourt, Mary McKernan McKay · 2022 to 2026
$7.2M
FIC NIH HHS D43 TW012275
6 · The paper itself

Abstract

Kawempe National Referral Hospital (KNRH) is a tertiary facility with over 21,000 pregnant or postpartum women admitted annually. The hospital, located in Kampala, Uganda, uses an Electronic Medical Records (EMR) system to capture patient data. Used since 2017, this readily available electronic health record (EHR) has the benefit of informing real-time clinical care, especially during pandemics such as COVID-19. We investigated the use of EHR to assess risk factors for adverse pregnancy and infant outcomes that can be incorporated into a data visualization dashboard for real time decision making during pandemics. This study analysed data from the UgandaEMR collected at pre-, during- and post-lockdown timepoints of the COVID-19 pandemic to determine its use in monitoring risk factors for adverse pregnancy and neonatal outcomes. Logistic regression models were used to identify the risk factors for adverse pregnancy and maternal outcomes including prematurity, obstetric complications, still births and neonatal deaths. Pearson chi-square test was used for pair-wise comparison of the outcomes at the various stages of the pandemic. Data analysis was performed in R, within the International COVID-19 Data Alliance (ICODA) workbench. A visualisation dashboard was developed based on the risk factors, to support decision making and improved healthcare delivery. Comparison of pre-and post-lockdown variables showed an increased risk of pre-term birth (adjusted Odds Ratio (aOR = 1.67, 95% confidence interval (CI) 1.38-2.01)); obstetric complications (aOR = 2.77, 95% CI: 2.53-3.03); immediate neonatal death (aOR = 3.89, 95% CI 2.65-5.72) and Caesarean section (aOR = 1.22, 95% CI 1.11-1.34). The significant risk factors for adverse outcomes were younger maternal age and gestational age <32weeks at labour. This study demonstrates the feasibility of using EHR to identify and monitor at-risk subpopulation groups accessing health services in real time. This information is critical for the development of timely and appropriate interventions in outbreaks and pandemic situations.

Identifiers

PMID38064420
PMCPMC10707482
OpenAlexW4389475759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.