ArticleAmerican journal of respiratory and critical care medicine2024
17q21 Variants Disturb Mucosal Host Defense in Childhood Asthma.
Erratum issuedOpen access · hybridAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 23 citations in OpenAlex.
- Unmasking programmed cell death in rhinovirus-driven asthma pathology.Biochemical Society transactions · 2026Review
- Nasal Epithelial Immune Signatures Are Associated With Age-Dependent Asthma Trajectories in Early Life.Allergy · 2026Observational
- Mechanisms and therapeutic strategies of asthma: from bench to bedside.Signal transduction and targeted therapy · 2026Review
- Increased high sensitivity C-reactive protein in more severe wheeze/asthma phenotypes in child- and adulthood in ALLIANCE.Respiratory research · 2026Observational
- Estimating in silico causal effects of DNA methylation on gene expression through genetic anchors in airway epithelium in asthma.Science advances · 2026Article
- Maternal smoking and CC-16: implications for lung development and COPD across the lifespan.American journal of respiratory and critical care medicine · 2026Article
- Triggering mechanisms of acute thunderstorm asthma: epithelial barrier disruption and immune dysregulation.Respiratory research · 2026Review
- Gasdermin family: a promising therapeutic target for asthma.Frontiers in medicine · 2026Review
- Network pharmacology identifies AKR1C3 and KYNU as potential targets of Astragalus Membranaceus and Ephedra in pediatric obesity-associated asthma.Scientific reports · 2025Article
- Child Opportunity Index at birth and asthma with recurrent exacerbations in the US ECHO program.The Journal of allergy and clinical immunology · 2025Article
- Airway Epithelium Derived from Induced Pluripotent Stem Cells to Model Asthma Susceptibility Loci.American journal of respiratory and critical care medicine · 2025Article
- Independent association of a 17q21 variant with exacerbations in type 2-low adult asthma.The journal of allergy and clinical immunology. Global · 2025Article
- Association of 17q12-q21 Asthma Risk Locus with Clinical Severity of Infant Respiratory Syncytial Virus Infection.Biomolecules · 2025Article
- Targeting respiratory virus-induced reactive oxygen species in airways diseases.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Defining the Blood Cytokine Profile in Asthma to Understand Asthma Heterogeneity.Immunity, inflammation and disease · 2025Article
- Mechanistic modelling of allergen-induced airways disease in early life.Scientific reports · 2025Article
- Baseline type 2 biomarker levels and clinical remission predictors in children with asthma.Frontiers in immunology · 2025Article
- Erratum: Missing Funder in "17q21 Variants Disturb Mucosal Host Defense in Childhood Asthma".American journal of respiratory and critical care medicine · 2024Article
- PGAP3 regulates human bronchial epithelial cell mRNAs present in asthma and respiratory virus reference data sets.medRxiv : the preprint server for health sciences · 2024Article
- Erratum: 17q21 Variants Disturb Mucosal Host Defense in Childhood Asthma.American journal of respiratory and critical care medicine · 2024Article
Corrections and comments
- Commented on by
- Erratum issued
- Erratum issued
Authors and funding
28 authors at 10 institutions in 5 countries.
Constanze A JakwerthCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.ORCID 0000-0002-2902-0393
Markus WeckmannMember of the German Center for Lung Research (DZL), Germany.
Sabina IlliMember of the German Center for Lung Research (DZL), Germany.
Helen CharlesCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.
Ulrich M ZisslerCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.
Madlen OelsnerCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.
Ferdinand GuerthCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.
Jimmy OmonyMember of the German Center for Lung Research (DZL), Germany.
Sai Sneha Priya NemaniMember of the German Center for Lung Research (DZL), Germany.
Ruth GrychtolMember of the German Center for Lung Research (DZL), Germany.ORCID 0000-0002-8084-104X
Anna-Maria DittrichMember of the German Center for Lung Research (DZL), Germany.ORCID 0000-0002-9582-1025
Chrysanthi SkevakiMember of the German Center for Lung Research (DZL), Germany.
Svenja FothMember of the German Center for Lung Research (DZL), Germany.
Stefanie WeberMember of the German Center for Lung Research (DZL), Germany.
Miguel A Alejandre AlcazarMember of the German Center for Lung Research (DZL), Germany.
Silke van Koningsbruggen-RietschelMember of the German Center for Lung Research (DZL), Germany.
Robert BrockMember of the German Center for Lung Research (DZL), Germany.
Samira BlauMember of the German Center for Lung Research (DZL), Germany.
Gesine HansenMember of the German Center for Lung Research (DZL), Germany.
Thomas BahmerMember of the German Center for Lung Research (DZL), Germany.
Klaus F RabeMember of the German Center for Lung Research (DZL), Germany.
Folke BrinkmannMember of the German Center for Lung Research (DZL), Germany.
Matthias Volkmar KoppDepartment of Pediatric Pneumology and Allergology, University Medical Center Schleswig-Holstein, Lübeck, Germany.
Adam M ChakerCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.
Bianca SchaubMember of the German Center for Lung Research (DZL), Germany.ORCID 0000-0003-1652-8873
Erika von MutiusMember of the German Center for Lung Research (DZL), Germany.
Carsten B Schmidt-WeberCenter of Allergy and Environment (ZAUM), Technical University and Helmholtz Center Munich, Munich, Germany.ORCID 0000-0002-3203-8084
ALLIANCE Study Group as part of the German Center for Lung Research
Helmholtz Zentrum München · DEUniversity Hospital Schleswig-Holstein · DEUniversity of Cologne · DECenter for Environmental Health · USMedizinische Hochschule Hannover · DEPhilipps University of Marburg · DEChristian-Albrechts-Universität zu Kiel · DEGerman Center for Lung Research · DEInstitut für Urheber- und Medienrecht · DEUniversity of Bern · CH
Funding
Bavarian State Office for Health and Food Safety K1-2497-GLB-20-V4Deutsche Forschungsgemeinschaft 197785619Deutsche Forschungsgemeinschaft 284237345Deutsche Forschungsgemeinschaft 428518790German Center of Lung Research (DZL) funded by the Federal Ministry of Education and Research (BMBF)Stiftung für Pathobiochemie und Molekulare Diagnostik
Abstract
PubMed holds no abstract for this paper.
Indexed as
AsthmaAdolescentAdultAged, 80 and overAllelesChildChild, PreschoolGenetic Predisposition to DiseaseGenotypeHumansInfantPhenotypePolymorphism, Single NucleotideRNA, MessengerYoung AdultRNA, MessengerALLIANCEasthmanasal transcriptomepreschool wheeze
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.