Evidence map›Paper›PMID 38064158›Full record

ArticleInfection2024

Population of invasive group A streptococci isolates from a German tertiary care center is dominated by the hypertoxigenic virulent M1

Manuel Wolters, Benjamin Berinson, Nicole Degel-Brossmann, Armin Hoffmann, Rico Bluszis, Martin Aepfelbacher, Holger Rohde, Martin Christner

Open access · hybridAbstract read
In one paragraph

Article in Infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Whole Genome Sequencing Analysis of Group AJournal of Korean medical science · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Post-pandemic upsurge in Group AMicrobiology spectrum · 2025
    Article
  10. Trends in the growing impact of group A Streptococcus infection on public health after COVID-19 pandemic: a multicentral observational study in Okayama, Japan.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Observational
  11. Characterization ofMicroorganisms · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Divergent effects ofJournal of clinical microbiology · 2024
    Article
  18. Molecular characterization ofMicrobial genomics · 2024
    Article
  19. Increase in invasiveEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Manuel WoltersInstitut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0002-1574-2598
Benjamin BerinsonInstitut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0003-2749-1201
Nicole Degel-BrossmannInstitut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.
Armin HoffmannInstitut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.
Rico BluszisInstitut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.
Martin AepfelbacherInstitut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.
Holger RohdeInstitut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany. rohde@uke.de.ORCID http://orcid.org/0000-0001-8587-4433
Martin ChristnerInstitut für Medizinische Mikrobiologie, Virologie und Hygiene, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0002-8538-0609
Universität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHypertoxigenic Streptococcus pyogenes emm1 lineage M1

methodsWhole-genome sequencing was employed to characterize a collection of 47 consecutive non-copy isolates recovered from blood cultures (21) and tissue samples (26) in our laboratory between October 2022 and April 2023.

resultsM protein gene (emm) typing distinguished 14 different emm types, with emm1 (17) being the dominant type. Single-nucleotide polymorphism (SNP) analysis confirmed the presence of all 27 SNPs characteristic for the M1

conclusionThis study has shown for the first time that M1

Indexed as

Streptococcal InfectionsStreptococcus pyogenesAntigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsGenotypeHumansTertiary Care CentersUnited KingdomAntigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsEmm typeEpidemiologyM1UKStreptococcus pyogenes

Identifiers

PMID38064158
PMCPMC10954911
OpenAlexW4389484265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.