Evidence map›Paper›PMID 38064121›Full record

ArticleArchives of pharmacal research2023

Physiologically based pharmacokinetic (PBPK) modeling to predict the pharmacokinetics of irbesartan in different CYP2C9 genotypes.

Chang-Keun Cho, Pureum Kang, Choon-Gon Jang, Seok-Yong Lee, Yun Jeong Lee, Chang-Ik Choi

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of pharmacal research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chang-Keun Cho *School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Pureum Kang *School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Choon-Gon JangSchool of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Seok-Yong LeeSchool of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea. sylee@skku.edu.ORCID http://orcid.org/0000-0003-4162-1981
Yun Jeong LeeCollege of Pharmacy, Dankook University, Cheonan, 31116, Republic of Korea.
Chang-Ik ChoiCollege of Pharmacy, Dongguk University-Seoul, Goyang, 10326, Republic of Korea. cichoi@dongguk.edu.
Sungkyunkwan University · KRDankook University · KRDongguk University · KR

Funding

National Research Foundation of Korea NRF-2019R1A2C1004582
6 · The paper itself

Abstract

Irbesartan, a potent and selective angiotensin II type-1 (AT

Indexed as

Angiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsCytochrome P-450 CYP2C9GenotypeHumansIrbesartanModels, BiologicalAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsCYP2C9 protein, humanCytochrome P-450 CYP2C9IrbesartanAntihypertensive pharmacotherapyCYP2C9Genetic polymorphismIrbesartanPhysiologically based pharmacokinetic (PBPK) model

Identifiers

PMID38064121
OpenAlexW4389479477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.