Evidence map›Paper›PMID 38064044›Full record

ArticleJournal of cardiovascular translational research2024

ALK1 Deficiency Impairs the Wound-Healing Process and Increases Mortality in Murine Model of Myocardial Infarction.

Shreyas Bhave, Lija Swain, Xiaoying Qiao, Gregory Martin, Tejasvi Aryaputra, Kay Everett, Navin K Kapur

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Discovery ofDiagnostics (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shreyas BhaveMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA, 02111, USA.ORCID 0000-0003-0393-0978
Lija SwainMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA, 02111, USA.
Xiaoying QiaoMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA, 02111, USA.
Gregory MartinMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA, 02111, USA.
Tejasvi AryaputraMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA, 02111, USA.
Kay EverettMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA, 02111, USA.
Navin K KapurMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA, 02111, USA. nkapur@tuftsmedicalcenter.org.
Tufts Medical Center · US

Funding

Mechanical Unloading and Delayed Reperfusion Promotes Myocardial Recovery after Acute Myocardial InfarctionR01HL139785 · NHLBI · TUFTS MEDICAL CENTER · PI KAPUR, NAVIN KUMAR · 2018 to 2021
$2.9M
Endoglin: A New Target of Therapy for Heart FailureR01HL133215 · NHLBI · TUFTS MEDICAL CENTER · PI KAPUR, NAVIN KUMAR · 2016 to 2020
$2.2M
NHLBI NIH HHS R01 HL133215NHLBI NIH HHS R01 HL139785
6 · The paper itself

Abstract

The functional role of TGFβ type I receptor, activin-like kinase (ALK)-1 in post-myocardial infarction (MI) cardiac remodeling is unknown. We hypothesize that reduced ALK1 activity reduces survival and promotes cardiac fibrosis after MI. MI was induced in wild-type (WT), and ALK

Indexed as

Activin Receptors, Type IIDisease Models, AnimalFibrosisMice, Inbred C57BLMice, KnockoutMyocardial InfarctionMyocardiumSignal TransductionVentricular Function, LeftVentricular RemodelingActivin Receptors, Type IAnimalsMaleSmad3 ProteinTime FactorsActivin Receptors, Type IActivin Receptors, Type IIAcvrl1 protein, mouseSmad3 ProteinSmad3 protein, mouseActivin-like kinase 1Bone morphogenetic protein 9FibrosisMyocardial infarction

Identifiers

PMID38064044
OpenAlexW4389489791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.