Evidence map›Paper›PMID 38064012›Full record

ReviewWorld journal of pediatrics : WJP2024

Expert consensus on the diagnosis, treatment, and prevention of respiratory syncytial virus infections in children.

Xian-Li Zhang, Xi Zhang, Wang Hua, Zheng-De Xie, Han-Min Liu, Hai-Lin Zhang, Bi-Quan Chen, Yuan Chen, Xin Sun, Yi Xu and 15 more

Erratum issuedOpen access · hybridAbstract readReviewConsensus Statement
In one paragraph

Review in World journal of pediatrics : WJP, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 4 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.

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  13. [Epidemiology, Mechanisms, and Clinical Challenges of Respiratory Syncytial Virus Co-infections in Children].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 18 institutions in 2 countries.

Xian-Li ZhangDepartment of Infectious Disease, Children's Hospital, Zhejiang University School of Medicine, 3333 Binsheng Road, Binjiang District, Hangzhou, 310052, China.
Xi ZhangClinical Research Unit, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang HuaDepartment of Infectious Disease, Children's Hospital, Zhejiang University School of Medicine, 3333 Binsheng Road, Binjiang District, Hangzhou, 310052, China.
Zheng-De XieBeijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Han-Min LiuDepartment of Pediatric Pulmonology, West China Second University Hospital, Sichuan University, Chengdu, China.
Hai-Lin ZhangDepartment of Pediatric Pulmonology, the Second Affiliated Hospital & Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
Bi-Quan ChenDepartment of Infectious Disease, Anhui Provincial Children's Hospital, Hefei, China.
Yuan ChenDepartment of Pediatrics, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
Xin SunDepartment of Pediatrics, Xijing Hospital, the Fourth Military Medical University, Xi'an, China.
Yi XuDepartment of Infectious Disease, Guangzhou Women and Children's Medicine Center, Guangzhou Medicine University, Guangzhou, China.
Sai-Nan ShuDepartment of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shun-Ying ZhaoDepartment of Respiratory Disease, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Yun-Xiao ShangDepartment of Pediatric Respiratory, Shengjing Hospital of China Medical University, Shenyang, China.
Ling CaoRespiratory Department, Children's Hospital Affiliated to Capital Institute of Pediatrics, Beijing, China.
Yan-Hui JiaDepartment of Infectious Disease, Children's Hospital, Zhejiang University School of Medicine, 3333 Binsheng Road, Binjiang District, Hangzhou, 310052, China.
Luo-Na LinDepartment of Infectious Disease, Children's Hospital, Zhejiang University School of Medicine, 3333 Binsheng Road, Binjiang District, Hangzhou, 310052, China.
Jiong LiDepartment of Clinical Epidemiology, Aarhus University, Aarhus, Denmark.
Chuang-Li HaoDepartment of Respirology, Children's Hospital of Soochow University, Suzhou, China.
Xiao-Yan DongDepartment of Respiratory, Children's Hospital of Shanghai, Children's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Dao-Jiong LinDepartment of Infectious Disease, Hainan Women and Children's Medical Center, Haikou, China.
Hong-Mei XuDepartment of Infectious Disease, Children's Hospital of Chongqing Medical University, Chongqing, China.
De-Yu ZhaoDepartment of Respiratory, Children's Hospital of Nanjing Medical University, Nanjing, China.
Mei ZengDepartment of Infectious Diseases, Children's Hospital of Fudan University, 399 Wanyuan Road, Minhang District, Shanghai, 201102, China. zengmeigao@aliyun.com.
Zhi-Min ChenDepartment of Respiratory Diseases, Children's Hospital, Zhejiang University School of Medicine, 3333 Binsheng Road, Binjiang District, Hangzhou, 310052, China. zmchen@zju.edu.cn.
Li-Su HuangDepartment of Infectious Disease, Children's Hospital, Zhejiang University School of Medicine, 3333 Binsheng Road, Binjiang District, Hangzhou, 310052, China. lisuhuang@zju.edu.cn.
Children's Hospital of Zhejiang University · CNBeijing Children’s Hospital · CNXinHua Hospital · CNAarhus University · DKAir Force Medical University · CNAnhui Provincial Children's Hospital · CNCapital Institute of Pediatrics · CNChildren's Hospital of Fudan University · CNChina Medical University · CNChongqing Medical University · CNGuangzhou Women and Children Medical Center · CNSecond Affiliated Hospital of Nanjing Medical University · CNSecond Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University · CNSecond Hospital of Hebei Medical University · CNShanghai Children's Hospital · CNSoochow University · CNTongji Hospital · CNWest China Second University Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) is the leading global cause of respiratory infections and is responsible for about 3 million hospitalizations and more than 100,000 deaths annually in children younger than 5 years, representing a major global healthcare burden. There is a great unmet need for new agents and universal strategies to prevent RSV infections in early life. A multidisciplinary consensus development group comprising experts in epidemiology, infectious diseases, respiratory medicine, and methodology aims to develop the current consensus to address clinical issues of RSV infections in children. DATA SOURCES: The evidence searches and reviews were conducted using electronic databases, including PubMed, Embase, Web of Science, and the Cochrane Library, using variations in terms for "respiratory syncytial virus", "RSV", "lower respiratory tract infection", "bronchiolitis", "acute", "viral pneumonia", "neonatal", "infant" "children", and "pediatric".

resultsEvidence-based recommendations regarding diagnosis, treatment, and prevention were proposed with a high degree of consensus. Although supportive care remains the cornerstone for the management of RSV infections, new monoclonal antibodies, vaccines, drug therapies, and viral surveillance techniques are being rolled out.

conclusionsThis consensus, based on international and national scientific evidence, reinforces the current recommendations and integrates the recent advances for optimal care and prevention of RSV infections. Further improvements in the management of RSV infections will require generating the highest quality of evidence through rigorously designed studies that possess little bias and sufficient capacity to identify clinically meaningful end points.

Indexed as

BronchiolitisRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsChildConsensusHospitalizationHumansRespiratory Syncytial VirusesConsensus preventionRespiratory syncytial virusTreatment

Identifiers

PMID38064012
PMCPMC10828005
OpenAlexW4389485303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.