Evidence map›Paper›PMID 38063644›Full record

ArticleHealthcare (Basel, Switzerland)2023

Effects of Different Protocols of Moderate-Intensity Intermittent Hypoxic Training on Mental Health and Quality of Life in Brazilian Adults Recovered from COVID-19: The AEROBICOVID Double-Blind Randomized Controlled Study.

Eugenio Merellano-Navarro, Marta Camacho-Cardenosa, Gabriel Peinado Costa, Ester Wiggers, Germano Marcolino Putti, Jonatas Evandro Nogueira, Elisangela Aparecida da Silva Lizzi, Átila Alexandre Trapé

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eugenio Merellano-NavarroDepartment of Physical Activity Sciences, Faculty of Education Sciences, Universidad Católica del Maule, Talca 3460000, Chile.ORCID 0000-0002-1557-2285
Marta Camacho-CardenosaClinical Management Unit of Endocrinology and Nutrition-GC17, Maimónides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofía University Hospital, 14004 Córdoba, Spain.ORCID 0000-0002-0921-2670
Gabriel Peinado CostaSchool of Physical Education and Sport of Ribeirao Preto, University of Sao Paulo (USP), Ribeirao Preto 14040900, SP, Brazil.ORCID 0000-0003-0687-6671
Ester WiggersRibeirao Preto Medical School, University of Sao Paulo (USP), Ribeirao Preto 14040900, SP, Brazil.
Germano Marcolino PuttiSchool of Physical Education and Sport of Ribeirao Preto, University of Sao Paulo (USP), Ribeirao Preto 14040900, SP, Brazil.ORCID 0000-0001-8191-598X
Jonatas Evandro NogueiraSchool of Physical Education and Sport of Ribeirao Preto, University of Sao Paulo (USP), Ribeirao Preto 14040900, SP, Brazil.
Elisangela Aparecida da Silva LizziAcademic Department of Mathematics, Federal University of Technology-Paraná, Cornélio Procópio 86300000, PR, Brazil.ORCID 0000-0001-7064-263X
Átila Alexandre TrapéSchool of Physical Education and Sport of Ribeirao Preto, University of Sao Paulo (USP), Ribeirao Preto 14040900, SP, Brazil.ORCID 0000-0001-6487-8160

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the effects of different protocols of moderate-intensity intermittent hypoxic training in patients who had recovered from COVID-19 on quality of life (QoL) and mental health. The sample of this clinical trial-controlled double-blind study consisted of 67 participants aged 30-69 years, who were organized randomly according to Normoxia, Hypoxia, Hypoxia Recovery or Control Group. Eight weeks of cycle ergometer training were performed with a frequency of three training sessions per week in normoxic or hypoxic conditions (with or without hypoxic recovery). Health-related QoL and Mental Health Status were evaluated by 12-Item Short Form Survey and Depression Anxiety and Stress Scale instruments, respectively. All training groups improved the QoL's physical dimensions (Baseline-Post: Normoxia Group 42.1 (11.0)-48.7 (7.0), Hypoxia Group 46.9 (11.8)-53.5 (6.6) and Hypoxia Recovery Group 45.8 (9.2)-51.1 (5.3)) and mental dimensions (Baseline-Post: Normoxia Group 48.8 (7.9)-54.6 (4.6), Hypoxia Group 45.2 (7.7)-53.2 (3.8) and Hypoxia Recovery Group 46.5 (9.7)-52.0 (9.9)). Regarding mental health outcomes, all training groups decreased depressive symptoms (66.7% Normoxia, 31.2% Hypoxia Recovery and 31% Hypoxia groups), anxiety symptoms (46.5% Normoxia, 45.9% Hypoxia Recovery and 39.5% in the Hypoxia groups) and stress symptoms (40.6% Normoxia, 36.3% Hypoxia Recovery and 22.1% Hypoxia groups). Significant statistical difference was not found between groups. Normoxic and hypoxic training showed a similar effect on QoL and the mental health of Brazilian adults who had recovered from COVID-19.

Indexed as

COVID-19depressionhypoxic trainingmental healthphysical exercisequality of life

Identifiers

PMID38063644
PMCPMC10706627

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.