ArticleHealthcare (Basel, Switzerland)2023
Association of Vitamin B12 Levels with Sleep Quality, Insomnia, and Sleepiness in Adult Primary Healthcare Users in Greece.
Article in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Association of Vitamin D and B12 Levels with Actigraphic Sleep in Cognitively Unimpaired Middle-Aged and Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Clinical effectiveness and economic evaluation of acupoint injection for the treatment of primary insomnia: a systematic review and network meta-analysis.Cost effectiveness and resource allocation : C/E · 2026Article
- Nutritional Interventions for Enhancing Sleep Quality: The Role of Diet and Key Nutrients in Regulating Sleep Patterns and Disorders.Food science & nutrition · 2025Review
- Association of Vitamin B12 Status with Polysomnographic Parameters and Cardiovascular Disease in Patients with Obstructive Sleep Apnoea.Nutrients · 2025Article
- Sleep Assessment in Patients with Inner Ear Functional Disorders: A Prospective Cohort Study Investigating Sleep Quality Through Polygraphy Recordings.Audiology research · 2025Article
- Glycemic status and macronutrient intake as predictors of sleep outcomes: an analysis of NHANES 2007-2020 data.Frontiers in nutrition · 2025Article
- Causal Relationship Between Micronutrient and Sleep Disorder: A Mendelian Randomization Study.Nature and science of sleep · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite vitamin B12's recognized importance for the nervous system, there is still a lack of research on the association between vitamin B12 and sleep, especially in primary care settings. We assessed vitamin B12 levels in adult primary healthcare users and investigated correlations with sleep quality, insomnia, and sleepiness. In this cross-sectional study, 512 consecutive participants were included. Information regarding anthropometrics, socio-demographics, and medical history was obtained. The Epworth Sleepiness Scale (ESS), Athens Insomnia Scale (AIS), and Pittsburg Sleep Quality Index (PSQI) were used to quantify excessive daytime sleepiness (EDS), insomnia symptoms, and sleep quality, respectively. The median vitamin B12 was 342 (266, 446) pg/mL. After adjustments, vitamin B12 levels < 342 pg/mL showed significant associations with insomnia symptoms [OR (95% CI) 2.434 (1.331-4.452),
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Registered trials
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