Evidence map›Paper›PMID 38063332›Full record

ArticleJournal of proteome research2024

Lipidomics Profiling Reveals Differential Alterations after FAS Inhibition in 3D Colon Cancer Cell Culture Models.

Brian D Fries, Fernando Tobias, Yijia Wang, Joseph H Holbrook, Amanda B Hummon

Open access · greenAbstract read
In one paragraph

Article in Journal of proteome research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Mass Spectrometry-Based Applications of Spheroids in Cancer Biology.Annual review of analytical chemistry (Palo Alto, Calif.) · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Brian D FriesDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.
Fernando TobiasDepartment of Chemistry, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-4085-4188
Yijia WangDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.
Joseph H HolbrookOhio State Biochemistry Program, The Ohio State University, Columbus, Ohio 43210, United States.
Amanda B HummonDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.ORCID 0000-0002-1969-9013
The Ohio State University · USNorthwestern University · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Daniel G. Stover · 1985 to 2026
$132.3M
Spatial SILAC: Examining the Proteome in 3D Cell CulturesR01GM110406 · NIGMS · UNIVERSITY OF NOTRE DAME · PI HUMMON, AMANDA B. · 2014 to 2022
$3.0M
Quantitative top-down proteomics of human colorectal cancer cells and tumorsR01CA247863 · NCI · MICHIGAN STATE UNIVERSITY · PI HUMMON, AMANDA B., LIU, XIAOWEN · 2021 to 2025
$1.9M
NCI NIH HHS P30 CA016058NCI NIH HHS R01 CA247863NIGMS NIH HHS R01 GM110406
6 · The paper itself

Abstract

Cancerous cells synthesize most of their lipids

Indexed as

CeruleninColonic NeoplasmsFatty Acid SynthasesLipidomicsSpheroids, CellularCell Line, TumorFatty Acids, UnsaturatedHumansLipid MetabolismCeruleninFatty Acids, UnsaturatedFatty Acid Synthasesapoptosiscolon cancerFAS inhibitionferroptosislipidomicsspheroids

Identifiers

PMID38063332
PMCPMC11161555
OpenAlexW4389488563

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.