ArticleJournal of the American Heart Association2023
Associations Between Life's Essential 8 and Chronic Kidney Disease.
Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- Lifetime cumulative effect of reproductive factors, "Life's essential 8" health status and risk of chronic kidney disease: a nationwide prospective cohort study.BMC public health · 2026Article
- Life's Essential 8-Defined Cardiovascular Health and Mortality Risk in Cardiovascular-Kidney-Metabolic Health Stages 0-4: A Cohort Study.Journal of epidemiology and global health · 2026Article
- Occupational heat exposure and chronic kidney disease risk under climate warming: a retrospective cohort study of petrochemical workers with mechanistic insights.Environmental health : a global access science source · 2026Article
- Association of Life's Essential 8 with albuminuria in a Northern Chinese population: a cross-sectional study.Scientific reports · 2026Article
- Association of life's essential 8 with chronic respiratory disease mortality and lung health: a national cohort study.BMJ open respiratory research · 2026Article
- Life's Essential 8 and the Risk of Overall and Specific-Site Cancer Types: A Large-Scale Prospective Cohort Study.Cancer medicine · 2026Article
- Life's Essential 8 and Parkinson's Disease Risk: A Cross-Sectional Study Based on NHANES Data (2005-2018).Revista de neurologia · 2025Article
- U-shaped association of body roundness index with all-cause and cardiovascular mortality in individuals with chronic kidney disease.Renal failure · 2025Article
- Association between life's essential 8 and diabetic kidney disease: a population-based study.Renal failure · 2025Article
- Association between cardiovascular health defined by life's essential 8 and frailty among US adults: a cross-sectional study.BMC cardiovascular disorders · 2025Article
- Relationship between cardiovascular health and COPD andits impact on all-cause mortality in patients with COPD: analyses of NHANES 2005-2018.BMC pulmonary medicine · 2025Article
- Association of lifestyle modifications with frailty in older adults: A cross-sectional study using NHANES.The Journal of frailty & aging · 2025Article
- Article
- Cardiovascular Health, Genetic Susceptibility, and the Risk of Incident Autoimmune Disorders in the UK Biobank: A Prospective Cohort Study.Journal of the American Heart Association · 2025Article
- The Cardiovascular-Kidney Connection in the Hispanic/Latino Community.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Life's Essential 8, Cardiovascular Health, and CKD Progression among Hispanic/Latino Adults: The Hispanic Community Health Study/Study of Latinos Study.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Associations between life's essential 8 and arthritis among adults in United States: a national-wide longitudinal study.BMC public health · 2025Article
- Association between Two Cardiovascular Health Algorithms and Kidney Stones: A Nationwide Cross-sectional Study.European urology open science · 2025Article
- Association between the life's essential 8 health behaviors score and all-cause mortality in cardiovascular-kidney-metabolic syndrome patients.Frontiers in nutrition · 2025Article
- Dose-response relationship between Life's Essential 8 score and COPD risk: the NHANES cohort study 2007-2018.Frontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic kidney disease (CKD) is closely associated with cardiovascular disease. We aimed to examine the association of Life's Essential 8 (LE8), the recently updated measurement of cardiovascular health, with the prevalence of CKD among US adults. METHODS AND
resultsThis population-based cross-sectional study used data from the National Health and Nutrition Examination Survey from 2007 to 2018 and included adults aged ≥20 years. Multivariable logistic and restricted cubic spline models were used to assess the associations between LE8 and CKD. Among 24 960 participants, 4437 were determined to have CKD (weighted percentage, 14.11%). After the adjustment of potential confounders, higher LE8 scores were associated with reduced odds of CKD (odds ratio for each 10-point increase, 0.79 [95% CI, 0.76-0.83]), and a nonlinear dose-response relationship was observed. Similar patterns were also identified in the associations of health behavior and health factor scores with CKD. Meanwhile, higher scores for blood glucose (odds ratio, for each 10-point increase, 0.88 [95% CI, 0.87-0.90]) and blood pressure (odds ratio, for each 10-point increase, 0.92 [95% CI, 0.91-0.94]) in the LE8 component are significantly associated with a lower prevalence of CKD. The inversed association of LE8 score and CKD was significantly stronger among middle-aged, male, and coupled participants.
conclusionsLE8 was negatively associated with the prevalence of CKD in a nonlinear fashion. Promoting adherence to optimal cardiovascular health levels may be beneficial to reduce the burden of CKD.
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