Evidence map›Paper›PMID 38062550›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2024

Novel tetrahydronaphthalen-1-yl-phenethyl ureas: synthesis and dual antibacterial-anticancer activities.

Yusuf Akbaba, Fatma Necmiye Kacı, Mehmet Enes Arslan, Süleyman Göksü, Adil Mardinoğlu, Hasan Türkez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yusuf AkbabaDepartment of Basic Sciences, Faculty of Science, Erzurum Technical University, Erzurum, Turkey.
Fatma Necmiye KacıDepartment of Molecular Biology & Genetics, Faculty of Science, Erzurum Technical University, Erzurum, Turkey.
Mehmet Enes ArslanDepartment of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, Erzurum, Turkey.
Süleyman GöksüDepartment of Chemistry, Faculty of Science, Atatürk University, Erzurum, Turkey.
Adil MardinoğluScience for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, Sweden.
Hasan TürkezDepartment of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer and antibiotic-resistant bacterial infections are significant global health challenges. The resistance developed in cancer treatments intensifies therapeutic difficulties. In addressing these challenges, this study synthesised a series of N,N'-dialkyl urea derivatives containing methoxy substituents on phenethylamines. Using isocyanate for the efficient synthesis yielded target products

Indexed as

Antineoplastic AgentsBacterial InfectionsNeuroblastomaAnti-Bacterial AgentsHeLa CellsHumansMicrobial Sensitivity TestsStructure-Activity RelationshipUreaAnti-Bacterial AgentsAntineoplastic AgentsUreaAntibacterial activityanticancer activityisocyanatesN,N′-dialkyl ureaphenethylamine

Identifiers

PMID38062550
PMCPMC11721939

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.