ArticleBMC genomics2023
The phylogenomic landscape of extended-spectrum β-lactamase producing Citrobacter species isolated from surface water.
Article in BMC genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 7 citations in OpenAlex.
- Flood-derived sludge as a reservoir of viable opportunistic pathogens after the October 2024 DANA in Valencia (Spain).International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- From environmental reservoirs to clinical threats: the expanding resistome and genetic plasticity of Citrobacter spp.Infection · 2026Review
- TheInternational journal of molecular sciences · 2026Review
- Characterization and pathogenic mechanisms of aFrontiers in microbiology · 2026Article
- Genetic manipulation ofApplied and environmental microbiology · 2025Article
- Enhancing plasmid typing with MOB-typer: resolving IncP and other incompatibility group misclassifications inMicrobial genomics · 2025Article
- Uncovering antibiotic resistance: extended-spectrum beta-lactamase-producingFrontiers in microbiology · 2025Article
- The importance of "one health approach" to the AMR study and surveillance in Angola and other African countries.One health (Amsterdam, Netherlands) · 2024Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCitrobacter species are Gram-negative opportunistic pathogens commonly reported in nosocomial-acquired infections. This study characterised four Citrobacter species that were isolated from surface water in the North West Province, South Africa.
resultsPhenotypic antimicrobial susceptibility profiles of the isolates demonstrated their ability to produce the extended-spectrum β-lactamase (ESBL). Whole genomes were sequenced to profile antibiotic resistance and virulence genes, as well as mobile genetic elements. In silico taxonomic identification was conducted by using multi-locus sequence typing and average nucleotide identity. A pangenome was used to determine the phylogenomic landscape of the Citrobacter species by using 109 publicly available genomes. The strains S21 and S23 were identified as C. braakii, while strains S24 and S25 were C. murliniae and C. portucalensis, respectively. Comparative genomics and sequenced genomes of the ESBL-producing isolates consisted of n = 91; 83% Citrobacter species in which bla-
conclusionsThe emerging and genomic landscapes of these ESBL-producing Citrobacter species are of significant concern due to their dissemination potential in freshwater systems. The presence of these ESBL and multidrug-resistant (MDR) pathogens in aquatic environments is of One Health importance, since they potentially impact the clinical domain, that is, in terms of human health and the agricultural domain, that is, in terms of animal health and food production as well as the environmental domain.
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