Evidence map›Paper›PMID 38062330›Full record

ReviewDiscover nano2023

A review on selenium and gold nanoparticles combined photodynamic and photothermal prostate cancer tumors ablation.

Olumakinde Charles Omiyale, Mariama Musa, Adewunmi Ifeoluwa Otuyalo, Tolulope Judah Gbayisomore, Damilola Zainab Onikeku, Solomon Damilare George, Possible Okikiola Popoola, Olabimpe Oluwatoyin Olofin, Kelechi Franklin Umunnam, Patricia Okwuchi Nneji and 2 more

Abstract readReview
In one paragraph

Review in Discover nano, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Olumakinde Charles OmiyaleDepartment of Pharmacology, Toxicology, and Therapeutics, College of Medicine, University of Lagos, Lagos, Nigeria. 199096019@live.unilag.edu.ng.
Mariama MusaDepartment of Biomedical Engineering, University of Ghana, Legon, Ghana.
Adewunmi Ifeoluwa OtuyaloDepartment of Medicine and Surgery, College of Medicine, Ryazan State Medical University, Ryazan, Russia.
Tolulope Judah GbayisomoreDepartment of Anatomy, University of Medical Sciences, Ondo, Nigeria.
Damilola Zainab OnikekuDepartment of Health Promotion and Environmental Health Education, Faculty of Education, University of Ilorin, Ilorin, Nigeria.
Solomon Damilare GeorgeDepartment of Genomic Research, Fresenius Medical Care, Lexington, USA.
Possible Okikiola PopoolaDepartment of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
Olabimpe Oluwatoyin OlofinDepartment of Biochemistry, School of Life Science, Federal University of Technology, Akure, Nigeria.
Kelechi Franklin UmunnamDepartment of Medical Laboratory Science, Vision College of Medical Sciences and Health Technology, Mbaise, Nigeria.
Patricia Okwuchi NnejiDepartment of Biology Education, Faculty of Science Education, Niger Delta University, Amassoma, Nigeria.
Musa AdnanDepartment of Public Health and Healthcare, First Moscow State Medical University, Sechenov, Moscow, Russia.
Taiwo Temitope OgunjobiDepartment of Biochemistry, Faculty of Basic Medical Sciences, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The acceptance of nanoparticle technology in the quest for cancer treatment is due to its many potentials and possibilities of filling in the gaps in the limitations of the current treatment modalities. Insights into the possibilities of getting even more from this technology, as well as the synergistic properties of photothermal therapy (PTT) and photodynamic therapy (PDT)-the use of reactive oxygen species (ROS)-can also be exploited in the ablation of prostate cancer tumors. Therefore, the combination of gold and selenium photoactive nanoparticles as platforms for drug delivery via PTT/PDT in prostate cancer therapy, with a specific emphasis on the 'micro-carrier' based approach, was discussed and explored in this review under relevant subtopics ranging from understanding the complex chemistry and biology of the pharmacologically active Se/Au-containing agents to giving a thorough knowledge of these therapeutic agents' potential as a targeted and successful treatment strategy for prostate cancer by investigating the complex mechanisms behind their delivery, activation, and synergistic effects. Furthermore, this article presents a comprehensive overview of the current research environment, problems encountered, and future perspectives in the continuous war against prostate cancer.

Indexed as

Gold nanoparticlesNanoparticle therapyPhotodynamic therapyPhotothermal therapy (PTT)Polymer-based microcarriersProstate cancerReactive oxygen species (ROS)Selenium nanoparticles

Identifiers

PMID38062330
PMCPMC10704013

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.