Evidence map›Paper›PMID 38062232›Full record

ArticleScientific reports2023

Improving enteral nutrition tolerance and protein intake maybe beneficial to intensive care unit patients.

Ming Zhong, Yuzhen Qiu, Tingting Pan, Ruilan Wang, Yuan Gao, Xuebin Wang, Yingchuan Li, Zhaofen Lin, Zhixiong Wu, Jianguo Tang and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Interruption of enteral tube feeding during chest physiotherapy in critically ill adults: A scoping review.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ming Zhong *Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuzhen Qiu *Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tingting PanDepartment of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ruilan WangDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuan GaoDepartment of Emergency and Critical Care Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xuebin WangDepartment of Critical Care Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Yingchuan LiDepartment of Emergency and Critical Care Medicine, The Sixth People's Hospital of Shanghai, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhaofen LinDepartment of Emergency and Critical Care Medicine, Shanghai Changzhen Hospital, Shanghai, China.
Zhixiong WuDepartment of Emergency and Critical Care Medicine, Huadong Hospital, Shanghai, China.
Jianguo TangDepartment of Emergency and Critical Care Medicine, The Fifth People's Hospital of Shanghai, Shanghai, China.
Xiang LiDepartment of Emergency and Critical Care Medicine, Central Hospital of Minghang District, Shanghai, China.
Xuemin WangDepartment of Emergency and Critical Care Medicine, Central Hospital of Songjiang District, Shanghai, China.
Jiayu ZhangDepartment of Emergency and Critical Care Medicine, Central Hospital of Putuo District, Shanghai, China.
Gang FengDepartment of Emergency and Critical Care Medicine, Gongli Hospital of Pudong New Area, Shanghai, China.
Sheng WangDepartment of Emergency and Critical Care Medicine, The Tenth People's Hospital of Shanghai, Shanghai, China.
Xinyuan LuDepartment of Emergency and Critical Care Medicine, Shanghai Pudong New Area People's Hospital, Shanghai, China.
Ye GongDepartment of Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Hongping QuDepartment of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Erzhen ChenDepartment of Emergency, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. rjchenerzhen@163.com.

Funding

the Program for Outstanding Medical Academic Leaders and Clinical innovation Program in science and technology by Shengkang hospital development center SHD22021304
6 · The paper itself

Abstract

Enteral nutrition (EN) is important for critically ill patients. This study investigated the current situation of EN treatment in SHANGHAI intensive care units (ICUs). We hypothesized that improving EN practice in SHANGHAI may benefit the prognosis of ICU patients. Clinical information on EN use was collected using clinic information forms in 2019. The collected data included the patient's general clinical information, EN prescription status, EN tolerance status, and clinical outcomes. The observation time points were days 1, 3, and 7 after starting EN. A total of 491 patients were included. The proportion of EN intolerance (defined as < 20 kcal/kg/day) decreased, with rates of intolerance of 100%, 82.07%, 70.61%, and 52.23% at 1, 3, 7, and 14 days, respectively. Age, mNutric score, and protein intake < 0.5 g/kg/day on day 7 were risk factors for 28-day mortality.The EN tolerance on day 7 and protein intake > 0.5 g/kg/day on day 3 or day 7 might affect the 28-day mortality. Risk factors with EN tolerance on day 7 by logistic regression showed that the AGI grade on day 1 was a major factor against EN tolerance. The proportion of EN tolerance in SHANGHAI ICU patients was low. Achieving tolerance on day 7 after the start of EN is a protective factor for 28-day survival. Improving EN tolerance and protein intake maybe beneficial for ICU patients.

Indexed as

Critical CareEnteral NutritionChinaCritical IllnessHumansIntensive Care UnitsNutritional Status

Identifiers

PMID38062232
PMCPMC10703788

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.