ArticleAnalytical and bioanalytical chemistry2024
Determination of carbon in microplastics and single cells by total consumption microdroplet ICP-TOFMS.
Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- Integrating Flow Imaging Analysis and Single-Particle ICP-TOFMS for Comprehensive Micro- and Nanoplastic Characterization.Analytical chemistry · 2026Article
- Quantitative LA-ICP-MS Imaging of Elemental Distributions with Protein Correlation in 3D Tumor Models.Analytical chemistry · 2026Article
- A new elemental analytical approach for microplastic sum parameter analysis-ETV/ICP-MS with COAnalytical and bioanalytical chemistry · 2026Article
- COAnalytical and bioanalytical chemistry · 2026Article
- Sizing and quantification of micro- and nanoplastics by single particle ICP-MS: a comparison between quadrupole and high-resolution instruments.Frontiers in chemistry · 2026Article
- Frontier Technologies in Single-Cell Analysis: Synergistic Fusion of Droplet Printing and High-Performance Detection System.Analytical science advances · 2025Review
- Ions with Ions, Entities with Entities: A Proof-of-Concept Study Using the SELM-1 Yeast Certified Reference Material for Intra- and Extracellular Se Quantification via Single-Cell ICP-Mass Spectrometry.Analytical chemistry · 2025Article
- Critical evaluation of the potential of ICP-MS-based systems in toxicological studies of metallic nanoparticles.Analytical and bioanalytical chemistry · 2024Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Recently, spICP-MS analyses of microplastics have demonstrated that the detection capabilities of ICP-MS are sufficient to determine the size and composition of such materials. However, solution nebulization or microdroplet generation limits the sizes of droplets, microparticles, or cells that can be efficiently introduced into commonly used horizontal ICP-MS configurations. Therefore, we introduced the development of a downward-pointing ICP coupled to a time-of-flight mass spectrometer (ICP-TOFMS), which enables quantitative transport of large microdroplets (diameters up to 90 µm) into the ICP. Here, we report the capabilities of downward ICP-TOFMS for the quantitative analysis of single cells and microplastic particles. For calibration of element mass amount per particle or cell, microdroplets (70 µm diameter) composed of multielement solutions were measured by ICP-TOFMS. Microplastic beads (polystyrene) and spleenocyte cells were then also embedded in microdroplets and measured by ICP-TOFMS with ion optics optimized to determine the signals from
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.