ArticleNature communications2023
Near-infrared light-triggered prodrug photolysis by one-step energy transfer.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The trial behind it
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Who cites it
13 citing papers in PubMed.
- Bioorthogonal Photoactivation of 2-Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Photocaged abscisic acid enhances rice salt tolerance via sustained signaling and multilevel stress modulation.Pest management science · 2026Article
- Remote-Controlled Release of Nitric Oxide by Plasmonic Waveguide Coated With Metal-Organic Frameworks.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Panchromatic Photocatalysis using a Ruthenium Polypyridyl Complex.Journal of the American Chemical Society · 2026Article
- An orthogonal RNA aptamer for targeted RNA regulation in phase-separated subcellular compartments.Nature communications · 2026Article
- Recent advances in tumor-activated prodrug nanoparticles for cancer immunotherapy.Frontiers in immunology · 2026Review
- Photocleavable Systems for Cell Biology: Conceptual Design across Molecular Modalities.Chembiochem : a European journal of chemical biology · 2025Review
- Neutrophil-Inspired Film for Nonadhesive Capture of Tumor Cells through Synergistic Functionalization of Zwitterions and Aptamers.Chem & bio engineering · 2025Article
- Precision Photochemistry: Every Photon Counts.Angewandte Chemie (International ed. in English) · 2025Article
- Application of photodynamic activation of prodrugs combined with phototherapy in tumor treatment.Molecular cancer · 2025Review
- Conceptual expansion of photomedicine for spatiotemporal treatment methods.RSC medicinal chemistry · 2025Review
- Semi-Organic Artificial Photosynthetic System with Engineered Phenoxazinone Derivatives for Photocatalytic Hydrogen Production with Broadened Near-Infrared Light Harvesting.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Enhancing Precision in Photodynamic Therapy: Innovations in Light-Driven and Bioorthogonal Activation.Pharmaceutics · 2024Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prodrug photolysis enables spatiotemporal control of drug release at the desired lesions. For photoactivated therapy, near-infrared (NIR) light is preferable due to its deep tissue penetration and low phototoxicity. However, most of the photocleavable groups cannot be directly activated by NIR light. Here, we report a upconversion-like process via only one step of energy transfer for NIR light-triggered prodrug photolysis. We utilize a photosensitizer (PS) that can be activated via singlet-triplet (S-T) absorption and achieve photolysis of boron-dipyrromethene (BODIPY)-based prodrugs via triplet-triplet energy transfer. Using the strategy, NIR light can achieve green light-responsive photolysis with a single-photon process. A wide range of drugs and bioactive molecules are designed and demonstrated to be released under low-irradiance NIR light (100 mW/cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.