Evidence map›Paper›PMID 38061891›Full record

ArticleACS chemical neuroscience2023

Repurposing of the PET Probe Prototype PiB for Label and Radiation-Free CEST MRI Molecular Imaging of Amyloid.

Caiyu Zhuang, Beibei Chen, Shuohua Wu, Liang Xu, Xiaolei Zhang, Xinhui Zheng, Yue Chen, Yiqun Geng, Jitian Guan, Yan Lin and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Effects of arsenic exposure on blood trace element levels in rats and sex differences.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Caiyu ZhuangDepartment of Radiology, Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China.ORCID 0000-0001-7310-0756
Beibei ChenDepartment of Radiology, Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China.
Shuohua WuDepartment of Radiology, Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China.ORCID 0000-0002-0468-4062
Liang XuDepartment of Medical Imaging, Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, China.ORCID 0000-0002-6381-7267
Xiaolei ZhangDepartment of Radiology, Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China.
Xinhui ZhengDepartment of Radiology, Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China.
Yue ChenDepartment of Radiology, Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China.
Yiqun GengLaboratory of Molecular Pathology, Shantou University Medical College, Shantou 515041, China.
Jitian GuanDepartment of Radiology, Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China.ORCID 0000-0002-8910-7052
Yan LinDepartment of Radiology, Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China.
Alan H WilmanThe Department of Biomedical Engineering, University of Alberta, Edmonton, Alberta T6G 1H9, Canada.
Renhua WuDepartment of Radiology, Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China.
Shantou University · CNSun Yat-sen University · CNUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Positron emission tomography (PET) probes are specific and sensitive while suffering from radiation risk. It is worthwhile to explore the chemical emission saturation transfer (CEST) effects of the probe prototypes and repurpose them for CEST imaging to avoid radiation. In this study, we used

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAmyloidAmyloidogenic ProteinsAniline CompoundsAnimalsMagnetic Resonance ImagingMiceMice, TransgenicMolecular ImagingPositron-Emission TomographyThiazolesAmyloidAmyloid beta-PeptidesAmyloidogenic ProteinsAniline CompoundsThiazolesAlzheimer’s diseaseamyloidCEST MRIPET probePiBrepurposing

Identifiers

PMID38061891
PMCPMC10741654
OpenAlexW4389463266

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.