Evidence map›Paper›PMID 38060691›Full record

ArticleThe journal of physical chemistry. B2023

Studies of DNA 'Breathing' by Polarization-Sweep Single-Molecule Fluorescence Microscopy of Exciton-Coupled (iCy3)

Jack Maurer, Claire S Albrecht, Patrick Herbert, Dylan Heussman, Anabel Chang, Peter H von Hippel, Andrew H Marcus

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Studies of DNA breathing in exciton-coupled (iCy3)Proceedings of SPIE--the International Society for Optical Engineering
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jack MaurerCenter for Optical, Molecular and Quantum Science, University of Oregon, Eugene, Oregon 97403, United States.
Claire S AlbrechtCenter for Optical, Molecular and Quantum Science, University of Oregon, Eugene, Oregon 97403, United States.
Patrick HerbertCenter for Optical, Molecular and Quantum Science, University of Oregon, Eugene, Oregon 97403, United States.
Dylan HeussmanCenter for Optical, Molecular and Quantum Science, University of Oregon, Eugene, Oregon 97403, United States.
Anabel ChangDepartment of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403, United States.
Peter H von HippelInstitute of Molecular Biology, University of Oregon, Eugene, Oregon 97403, United States.
Andrew H MarcusCenter for Optical, Molecular and Quantum Science, University of Oregon, Eugene, Oregon 97403, United States.ORCID 0000-0003-2109-327X

Funding

STRUCTURE AND RELATIONS OF PROTEINS AND NUCLEIC ACIDSR01GM015792 · NIGMS · UNIVERSITY OF OREGON · PI MARCUS, ANDREW HADLEY · 1985 to 2025
$10.2M
NIGMS NIH HHS R01 GM015792
6 · The paper itself

Abstract

Local fluctuations of the sugar-phosphate backbones and bases of DNA (often called DNA 'breathing') play a variety of critical roles in controlling the functional interactions of the DNA genome with the protein complexes that regulate it. Here, we present a single-molecule fluorescence method that we have used to measure and characterize such conformational fluctuations at and near biologically important positions in model DNA replication fork constructs labeled with exciton-coupled cyanine [(iCy3)

Indexed as

DNADNA ReplicationMicroscopy, FluorescenceMolecular ConformationSpectrometry, FluorescenceDNA

Identifiers

PMID38060691
PMCPMC10754251

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.